异甘草酸镁治疗肝癌动脉栓塞化疗肝损伤的临床研究_陈玉强.pdfVIP

2010 14 17 Journal of Clinical Medicine in Practice 15 陈玉强, 洪节约, 张雅雅, 邱国钦, 郭春华 ( , , 361003) : ( TACE) TACE 105 , ( n 65) ( n 40) , , 2 TACE 3 d~ 7 d , TACE 2 d7 d ; 2 TACE TACE 2 d 2 ( TBIL) ( ALT) (AST) ( P 0. 05) ; 7 d ALTAST ( P 0. 05) , 7 d ALT AST ( P 0. 05) ; 2 TACE ( P 0. 05) , ( P 0. 05) TACE , TACE : ; ; ( T ACE) ; : R 7357 : A : 2010) A clinical research of magnesium isoglycyrrhizinate trerapy for liver lesion in transcatheter arterial chemoembolization CHEN Yuqiang, HONG Jieyue, HANGYaya, QIU Guoqin, GUO Chunhua (N o . 174 H osp ital of PLA , X iamen, F uj ian, 361003) ABSTRACT: Objective To explore the clinic effect of Magnesium isoglycyrrhizinate on the patients with primary hepatic carcinoma after transcatheter arterial chemoembolization ( TACE) . Methods 105 cases with malignant tumor complicated with liver lesion induced by TACE were randomly divided to receive magnesium isoglycyrrhizinate therapy ( treatment group) or diammoni- um glycyrrhizinate injection ( control group) with 150 mg iv gtt qd from Preoperative 3 days to the 7th day after TACE operation. The incidences of the adverse effect after TACE operation were memorized. Results T he levels of TBIL, ALT and AST on the 2nd day after TACE operation were higher than those before TACE operation in the two groups(P 0. 05) . The levels of ALT and AST on the 7th day after TACE operation were revivaled in the therapy group( P 0. 05) . But the levelsof ALT and AST in the control group on the 7th day were higher than those before TACE operation ( P 0. 05) . The index of the synthesis ability of hepatocyte was not improved in the therapy gr