抗运动性疲劳中药及其复方的研究进展-天津中草药杂志社.pdfVIP

• 446 • 现代药物与临床 Drugs Clinic 第 28 卷 第 3 期 2013 年 5 月 抗运动性疲劳中药及其复方的研究进展 1 2 3 3* 肖婷婷 ，郭 倩 ，田成旺 ，张铁军 1. 天津中医药大学，天津 300193 2. 天津医科大学，天津 300070 3. 天津药物研究院，天津 300193 摘 要：运动性疲劳属于中医学“劳”、“虚劳”的范畴，介绍了中医对运动性疲劳的认识及补益和调理相结合的治则，从调 节能源物质代谢、调节代谢产物、对自由基消除等方面总结多种中药抗疲劳的作用机制，并总结了一些抗疲劳复方的配伍依 据和抗疲劳现代药理研究进展，为开发延缓和消除运动性疲劳药物提供参考。 关键词：运动性疲劳；能源物质代谢；自由基消除；作用机制 中图分类号：R287 文献标志码：A 文章编号：1674 - 5515(2013)03 - 0446 - 06 DOI: 10.7501/j.issn.1674-5515.2013.03.047 Research progress in Chinese material medica and their compounds for treatment of exercise-induced fatigue 1 2 3 3 XIAO Ting-ting , GUO Qian , TIAN Cheng-wang , ZHANG Tie-jun 1. Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 2. Tianjin Medical University, Tianjin 300070, China 3. Tianjin Instiute of Pharmaceutical Research, Tianjin 300193, China Abstract: Exercise-induced fatigue belongs to the “overstrain”, “consumptive disease” in traditional Chinese medicine (TCM), this article expounds the understanding of TCM on the exercise-induced fatigue and the therapeutic principle of the combination of regulation and tonification, summarizes a variety of TCM anti-fatigue mechanism from the regulation of energy metabolism and metabolites, elimination of free radicals, and the modern pharmacological research progress in the compatibility of basis and fatigue resistance in some anti-fatigue prescriptions, so as to provide the references for the development of delaying and eliminating the drugs against the exercise-induced fatigue. Key words: exercise-induced fatigue; energy metabolism; elimination of free radicals; mechanism 运动性疲劳在中医学属于“劳”、“虚劳”的范 升降恢复平衡是机体抗运动性疲劳能力的有效方 畴，《内经·素问 ·举痛论》言：“劳则气耗”，即劳 法，从而形成了使用中药抗体力疲劳以补气助阳为 动或运动可导致机体阳气不足而引发肢软乏力、神