miRNA-34a在宫颈HPV持续感染患者脱落细胞中的表达及意义.pdfVIP

• 1282 • 陈贝贝，等 m iR N A -34a 在宫颈H P V 持续感染患者脱落细胞中的表达及意义 Research,2 0 0 1 ,6 1 (2 3 ) ：8586 -8 5 9 4 . produce tenascin C as a metastatic niche component to colonize [1 4 ] C R u iz ,W H uang,M E H e g i,e t al. D ifferential gene expression a­ the lungs[ J ] . Nature Medicine ,2 0 1 1 ,1 7 (7 ) ：867 - 874. nalysis reveals activation of growth promoting signaling pathways [1 7 ] Blaum ueller C M , Qi H , Zagouras P. Intracellular cleavage o f Notch by tenascin - C [ J ] . Cancer Research, 2 0 0 4 ,6 4 ( 20 ) 7377 ： - leads to a heterodimeric receptor on the plasma membrane [ J ] . 7385. C ell, 1 9 9 7 ,9 0 ：281 -2 9 1 . [1 5 ] 0 De W ever,Q D N guyen,L Van H oorde,et al. Tenascin - C and [1 8 ] Balasubramanian, Sivasankaran M D , Anthony G haffari, et al. Te­ S F/H G F produced by myofibroblasts in vitro provide convergent nascin - C is a novel RBPJK - induced target gene for notch sig­ pro - invasive signals to human colon cancer cells through RhoA naling in gliomas[ J ] . Cancer R es,2009 ,6 9 (2 ) ：458 -4 6 5 . and R a c [J ].F A S E B J ,2 0 0 4 ,1 8 (9 ) 1016 ： -1 0 1 8 . [1 6 ] T Oskarsson, S Acharyya, X H F Zhang, et al. Breast cancer cells (编校：张西敏） miRNA - 3 4 a 在宫颈HPV 持续感染患者脱落细胞中的表达及意义 陈贝贝1 ，于丽波1 ，孙文洲2 ，葛鲁倩1 ，赵欣瑶1 ，金 雁 1 Expression of m iR N A -34a in cervical exfoliated cells of HPV persistence infection and its clinical significance Chen Beibei1 ,Y u Libo1 ,Sun Wenzhou2,G e Luqian1 ,Zhao Xinyao1 ,Jin Yan1 1 Third Department of Gynecological Oncology ；2 Third Department o