应用“及时与多次”缩野技术预防小细胞肺癌放射性肺炎的临床研究-肿瘤学专业毕业论文.pdfVIP

Abstract Objective To investigate the value of using “timely and repeatedly”shrinking-field technique for preventing radiation pneumonitis(RP).Methods 52 patiens with histologic or cytologically proven small cell lung cancer were included in this study.Radiotherapy was delivered in 2Gy daily fraction to a total dose of 60Gy.All of sixteen patients received three times simulation CT scan.one repeat CT scan were performed at 30Gy and 50Gy at two repeat CT scan. According three CT data , three treamen plan were designed,called plan 、plan 、 plan , respectively. 1 2 3 Comparisons were executed between three plans in the changes of GTV、V 、V 、V 、V 、V 、V .Results The value of GTV and V were 5 10 15 20 25 30 dose all reduced obviously in plan and plan ,there were significant 2 3 difference in plan and plan (p＜0.05).Two patients occurred 1 2 radiation pneumonitis (RP),the ratio of RP is 11.5% in this research.Conclusions “Timely and repeatedly”shrinking-field technique likely decrease the ratio of RP in patients with SCLC ,and lately effect is better. Key words:Small cell lung cancer; Radiotherapy; Radiation pneumonitis; Shrinking-field;Prevention 3 万方数据 目 录 引言 ·····································································································4 第 1 章 材料与方法 ················