纤维支气管镜是诊断性和治疗性的过程通常在监护性麻醉mac下进行.docVIP

回复问题: 术前基础氧饱和度＜90%，肺功能FEV1＜1L，心动过缓（HR＜60次/分）的患者排除在外基氧饱和度＜90%）FEV1＜1L心动过缓（HR＜60次/分）100mmHg),高血压(收缩压≥140mmHg和（或）舒张压≥90mmHg）T0），分别记录麻醉后入声门前（T1）、气管镜入声门即刻（T2）、超声探头初次置入即刻（T3），取活检时（T4）、术毕即刻（T5）的心率（HR）、平均动脉压（MAP）、血氧饱和度（SpO2）、不良反应的发生率及患者苏醒时间。结果：在RP组，T1点的HR﹑MAP明显低于T0点（P0.05））））SpO2较基础值明显下降，与DP组相比有明显差异（P0.05）；DP组在T2时的呛咳发生率高于RP（P0.05））））右美托咪定异丙酚右美托咪血流动力学稳定Comparison of the efficacy of anesthesia with dexmedetomidine and remifentanil combined with propofol target-controlled infusion(TCI) for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) ZHU Hongwei ,WU jingxiang,XU Meiying.Department of Anesthesiology.Shanghai Chest Hospital，Shanghai jiaotong University，shanghai 200030,China 【Abstract】 objective To Compare of the efficacy of anesthesia with dexmedetomidine and remifentanil combined with propofol target-controlled infusion(TCI) for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Methods Sixty patients undergoing EBUS-TBNA were randomly assigned to a remifentanil-propofolgroup (Group RP,n=30) or a dexmedetomidine-propofol group (Group DP, n=30).In group RP, 0.5ug.kg-1 remifentanil was injected slowly , followed by infusion at 0.02 ug.kg-1.min-1;In group DP, dexmedetomidine 0.5ug.kg-1 was injected with 10 min,followed by infusion at 0.2ug.kg-1.h-1.In two groups the 作者单位：200030上海交通大学附属胸科医院麻醉科 通信作者：徐美英 myxu55@ initial propofol concentration of TCI was 1.5ug.ml-1, adjusting TCI concentration by the bispectral index(BIS) 40-50.The operation began until lost consciousness.Heart rate(HR), mean arterial pressure(MAP), pulse oxygen saturation(SpO2) were recorded before the anesthesia (T0)、before the examination after anesthesia (T1)、bronchoscope passed the glottis(T2)、the ultrasound probe insertion point(T3)、biopsy、 after bronchoscope pulled outadverse events and recovery times were also obtained.Results In group RP, HR and MAP at T1 were lower than those at T0(P0.05),but in group DP,Only HR at T1 was lower than that at T0(P