巴尔通体感染性心内膜炎的研究进展-微生物学报.PDFVIP

微生物学通报 Jan. 20, 2015, 42(1): 192−199 Microbiology China © 2015 by Institute of Microbiology, CAS tongbao@ DOI: 10.13344/j.microbiol.china.140375 专论与综述 巴尔通体感染性心内膜炎的研究进展 刘云彦1,2,3 栗冬梅1,3* 刘起勇1,3 陈忠科2* (1. 中国疾病预防控制中心传染病预防控制所 传染病预防控制国家重点实验室 北京 102206) (2. 山东大学 生命科学学院 山东 济南 250100) (3. 感染性疾病诊治协同创新中心 江苏 杭州 310003) 摘 要：感染性心内膜炎一直是威胁人类健康的重要疾病之一。近年来人类正面临着此病发病率 持续上升的局面，其诊断、治疗和预防依然是目前需要解决的重要临床和公共卫生问题。本文介 绍了感染性心内膜炎疾病的最新研究进展，分析了国内外报道的538 份巴尔通体感染性心内膜炎 的病例，重点阐述了巴尔通体和相关心内膜炎的流行病学、实验室诊断、治疗以及发病的危险因 素和预防控制措施。预测这些研究将对人类理解和控制巴尔通体感染性心内膜炎具有重要的指导 意义。 关键词：感染性心内膜炎，巴尔通体，实时荧光定量PCR ，诊断，猫抓病 Research progress on Bartonella endocarditis: a review of the literatures LIU Yun-Yan1,2,3 LI Dong-Mei1,3* LIU Qi-Yong1,3 CHEN Zhong-Ke2* (1. State Key Laboratory for Infectious Diseases Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China) (2. School of Life Science, Shandong University, Jinan, Shandong 250100, China) (3. Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, Jiangsu 310003, China) Abstract: Infective endocarditis (IE) remains one of the major diseases, which poses a serious threat to human health. In recent years, human being is facing an increased incidence rate of IE and therefore accurate diagnosis and effective treatment as well as preventive measurements become urgent clinical and public health is