【word】 糖尿病肾病患者自体动静脉内瘘的护理进展.docVIP

糖尿病肾病患者自体动静脉内瘘的护理进展 广东医学2012年2月第33卷第3期GuangdongMedicalJournalFeb.2012,Vo1.33,No.3 [15]wuJ,HUD,YANGG,eta1.Down—regulationofBMI一1coop— cratestllartemisininongrowthinhibitionofnasopharyngealcarci? nonlacells[J].JCellBiochem,2011,112(7):1938—1948. [16]SONGLB,ZENGMS,LIAOWT,eta1.Bmi一1isanovelmo- lecularmarkerofnasopharyngealcarcinomaprogressionandimmor- talizesprimaryhumannasopharyngealepithelialcells[J].Cancer Res,2006,66(12):6225—6232. [17]HES,IWASHITAT,BUCHSTALLERJ,eta1.Bmi一1over— expressioninneuralstem/progenitorcellsincreasesproliferation andneurogenesisinculturebuthaslittleeffectonthesefunctions invivo[J].DevBiol,2009,328(2):257—272. [18]DHAWANS,TSCHENSI,BHUSHANA.Bmi一1regulatesthe Ink4a/Arflocustocontrolpancreaticbeta—cellproliferation[J]. GenesDev,2009,23(8):906—911. [19]STYCZYNSKIJ,DREWAT.Leukemicstemcells:frommetabolic pathwaysandsignalingtoanewconceptofdmgresistancetarge— ting[J].ActaBiochimPal,2007,54(4):717—726. [20]WANGQ,LIWL,YOUP,eta1.OncopreteinBMI一1induces themalignanttransformationofHaCaTcells[J] 2009,106(1):16—24. ? 429? JCellBiochem [21]MOLOFSKYAV,HES,BYDONM,eta1.Bmi一1promotesneu— ralstemcellself—renew~andneuraldevelopmentbutnotmouse growthandsurvivalbyrepressingthepl61nk4aandpl9Arfsenes— cencepathways[J].GenesDev,2005,19(12):1432—1437. [22]SILVAJ,GARCIAJM,PENAC,eta1.Implicationofpolycomb membersBmi一1,Mel一18,andHpc一2intheregulationof pl61NK4a,pl4ARF,h—TERT,andc—Mycexpressioninpri— marybreastcarcinomas[J].ClinCancerRes,2006,12(23): 6929—6936. [23]杨小平,张星.青蒿琥酯诱导人肿瘤细胞凋亡及其分子机制 的探讨[J].中草药,2002,33(9):819—821. [24]SCHLEGELR,DISBROWGL,BAEGEAC,eta1.Dihydroarte— misininiscytotoxietopapillomavirus—expressingepithelialcells lnvitroandinvivo[J].CancerRes,2005,65(23):10854— 10861. (收稿13期:2011一O8一O3编辑:祝华) 糖尿病肾病患者自体动静脉内瘘的护理进展 童小珍,张广清 广东省中医院护理部(广州510120) 糖尿病肾病(diabeticnephropathy,DN)是糖尿病全身性 微血管并发症之一,也是糖尿病致死的主要原因.据统计, 我国DN已跃居终末期肾功能衰竭发病因素的第2位J. 目前,血液透析(hemodialysis,HD)仍是DN终末期肾功能衰 竭者最常用的肾脏替代治疗方法之一.动静脉内瘘(arterio. venousfistula,AVF)是为终末期肾病患者接受HD而建立的 永久性血管通道,是目前临床上最常用的HD血管通路J.