血小板增多症诊疗指南.docVIP

2011.06.19 李 端、黄 璐、袁碧芬、杨迪元、金颖康医生： ?????? 国际输血和血液学杂志编辑部送来几篇指南让我们编译，其中一篇是关于的，你们翻译，。叶铁真 Guideline for investigation and management of adults and children presenting with a thrombocytosis Claire N. Harrison,1 David Bareford,2 Nauman Butt,3 Peter Campbell,4 Eibhlean Conneally,5 Mark Drummond,6 Wendy Erber,7 Tamara Everington,8 Anthony R. Green,9 Georgina W. Hall,10 Beverley J. Hunt,1 Christopher A. Ludlam,11 Richard Murrin,12 Catherine Nelson-Piercy,1 Deepti H. Radia,1 John T. Reilly,13 Jon Van der Walt,1 Bridget Wilkins1 and Mary F. McMullin14 Writing group: British Committee for Standards in Haematology Keywords: essential thrombocythaemia, myeloproliferative disorder, myelofibrosis, MDS. Introduction The guideline group was selected to be representative of Ukbased medical experts. MEDLINE and EMBASE were searched systematically for publications in English from 1966 until October 2009 using a variety of key words. The writing group produced the draft guideline which was subsequently revised by consensus by members of the Haemostasis and Thrombosis and Haemato-oncology Task Forces of the British Committee for Standards in Haematology. The guideline was then reviewed by a sounding board of approximately 50 UK haematologists, the British Committee for Standards in Haematology (BCSH) and the British Society for Haematology Committee and comments incorporated where appropriate. Criteria used to quote levels and grades of evidence are as outlined in the Procedure for Guidelines Commissioned by the BCSH (Table I). The objective of this guideline is to provide healthcare professionals with clear guidance on the investigation and management of thrombocytosis in both adult and paediatric patients. The guidance may not be appropriate to all patients with thrombocytosis and in all cases individual patient circumstances may dictate an alternative approach. Table I. Evidence statements and grades of recommendations. Classification of evidence levels Ia: Evidence obtained from meta