MRI及DWI在新生儿低血糖脑损伤中的应用.docVIP

精品论文 参考文献 MRI及DWI在新生儿低血糖脑损伤中的应用 郭庆清 许祖梅 李梅芳 （莆田学院附属医院医学影像科 351100） 【摘要】目的 探讨新生儿低血糖脑损伤的MRI特征及扩散加权成像(DWI)在低血糖脑损伤诊断中的应用价值。方法　回顾性分析9例经临床确诊的新生儿低血糖脑损伤病例的MRI资料，所有病例均在出生后1～7d行MRI检查，扫描序列包括常规T1WI、T2WI及DWI序列。结果　9例患儿血糖水平在0.2～1.8mmol/l,平均约0.95mmol/l。常规T1WI表现为受累部位稍低信号4例，稍高信号1例；7例T2WI表现为受累部位稍高信号或灰白质分界不清。9例行DWI扫描均发现斑片状、条状及脑回样高信号，其中受累部位双侧顶枕叶皮层及皮层下白质8例，胼胝体受累5例，侧脑室旁脑白质受累4例，基底核受累2例，尾状核头部受累1例，所有患儿小脑及脑干均未见异常。结论　新生儿低血糖脑损伤以双侧枕顶叶后???脑组织及胼胝体压部最常受累，常对称性分布，具有一定特征性。DWI序列较常规T1WI及T2WI序列在低血糖脑损伤的诊断及评估上更具优越性。 【关键词】低血糖症 脑损伤 新生儿 磁共振成像 【中图分类号】R445 【文献标识码】A 【文章编号】2095-1752（2014）07-0061-02 The value of MRI and DWI in the diagnosis of neonatal hypoglycemic brain injury Guo Qingqing , XU Zumei , LI Meifang Department of Medical Imaging, The Affiliated Hospital of Putian University, Putian 351100 【Abstract】0bjective：To investigate MRI features of neonatal hypoglycemic brain injury(NHBI)and to explore the value of diffusion-weighted imaging (DWI)in the diagnosis of NHBI．Methods：MR imaging features of 9 neonates with NHB1 were retrospectively evaluated．All the neoates were performed 1～7 days of life with MRI sequences including TlWI，T2WI and DWI．Results：The level of blood glucose was 0.2～ 1.8mmol／l in 9 cases of neonatal hypoglycemia，an average about 0.95mmol／1. NHBI showed slight hypointensity(4 cases)and slight hyperintensity(1 cases)on TlWI and hyperintense(7cases)and poor gray-white differentiation on T2WI. All of the DWI imaging showed abnormalities；The parietal and occipital cortex and subcortical white matter abnornlalities occurred in 88.9%（8cases) of infants with hypoglycemia brain injury，corpus callosum abnormalities occurred in 55.6%(5cases)of intants with hypoglycemia brain injury;the periventricular white matter injury occurred in 44.4%(4cases)of infants with hypoglycemia brain injury;22.2%(2cases)ofinfants with hypoglycemia had basal ganglia abnormalities,and 11.1% (1case)had head of c