丙戊酸钠与左乙拉西坦治疗儿童癫痫病的疗效观察.docVIP

精品论文 参考文献 丙戊酸钠与左乙拉西坦治疗儿童癫痫病的疗效观察 朱长春(湖北省竹山县人民医院儿二科 442200) 　　【摘要】目的：通过比较丙戊酸钠和左乙拉西坦在儿童癫痫病治疗中的疗效，对治疗儿童癫痫的两种药物的疗效进行一个深入的了解和充分的认识，以期达到一个良好的治疗效果。方法：将笔者所在医院2013年01月-2014年01月收治的癫痫患儿70例随机地分为两组，每组35例，分别采用左乙拉西坦和丙戊酸钠进行治疗，观察并记录其治疗效果，数据用统计软件SPSS 11.0进行统计分析。结果：采用丙戊酸钠治疗的研究组中，4例无效，21例具有显著疗效，8例完全控制病情，治疗后病情加重2例，总有效率达82.8%；采用左乙拉西坦治疗的患儿经治疗后无明显效果3例，具有显著疗效23例，有5例病情完全控制，4例经治疗后病情加重，总的有效率达80%。两组数据的比较没有显著性差异（P＞0.05）。结论：在治疗儿童癫痫中，两种药物疗效相差无机，都是治疗儿童癫痫相对有效的药物，在临床治疗中均可使用。 　　【关键词】左乙拉西坦 丙戊酸钠 儿童癫痫 临床效果 　　【Abstract】objective: by comparing the sodium valproic acid and left b raschig efficacy in the treatment of epilepsy in children, the curative effect of two drugs in treating children epilepsy, an in-depth understanding and fully understanding, in order to achieve a good therapeutic effect. Methods: the authors hospital 01, 2013-01, 2014 children with epilepsy treated 70 cases randomly divided into two groups, each group of 35 cases, respectively, in left b raschig and valproate treatment, observe and record the treatment effect, the data with statistics software SPSS 11.0 statistical analysis. Results: valproate in the treatment group, 4 cases were invalid, 21 cases with significant curative effect, 8 cases of complete control of disease, disease progression after treatment in 2 cases, total effective rate was 82.8%; In left b raschig treatment of children after treatment has no obvious effect in 3 patients, 23 cases with significant curative effect, 5 cases of complete control, 4 cases of disease progression after treatment, the total efficiency of 80%. The comparison of two groups of data no significant difference (P gt; 0.05). Conclusion: in the treatment of epilepsy in children, two kinds of drug efficacy difference between inorganic and are relative effective drug treatment of epilepsy in children, can be used in clinical treatment. 　　【中图分类号】R720.5 【文献标识码】A 【文章编号】1672-5085（2014）06-0095-02 　　儿童癫痫在临床上十分常见，其具有遗传倾向明显，男性的发病率明显高于女性等特征，在儿童1-14