厄贝沙坦氢氯噻嗪复方片治疗难治性高血压的临床疗效.docVIP

精品论文 参考文献 厄贝沙坦氢氯噻嗪复方片治疗难治性高血压的临床疗效 资阳市人民医院 四川资阳 641300 　　摘要：目的：探究厄贝沙坦/氢氯噻嗪复方片治疗难治性高血压的临床疗效。方法：随机选取我院2015年7月至2016年7月收治的88例难治性高血压患者，将88例患者随机分为实验组与对照组，两组患者均给予氨氯地平以及美托洛尔常规治疗，其中实验组44例患者在常规治疗的基础上给予厄贝沙坦/氢氯噻嗪复方片治疗，对照组44例患者在常规治疗的基础上给予氢氯噻嗪治疗。比较两组患者临床治疗过程中血压变化情况以及不良反应的发生情况。结果：4周后实验组患者血压控制情况明显优于对照组，实验组患者有2例出现低血压，对照组有5例出现低血压，实验组患者不良反应发生率明显低于对照组（11.4%vs27.3%）。结论：对难治性高血压患者在常规药物治疗的基础上给予厄贝沙坦/氢氯噻嗪复方片治疗，可以有效控制患者血压，降低不良反应的发生率。 　　关键词：厄贝沙坦/氢氯噻嗪复方片；难治性高血压；临床疗效 　　Abstract Objective：To explore the clinical effect of irbesartan / hydrochlorothiazide compound in treating refractory hypertension.Methods：in our hospital from July 2015 to July 2016 treated 88 patients with refractory hypertension patients，88 patients were randomly divided into experimental and control groups，two groups of patients were treated with amlodipine and beauty care lol conventional treatment，the experimental group of 44 patients given irbesartan / hydrochlorothiazide in the conventional treatment based on a compound in the treatment，44 patients in the control group administered with hydrochlorothiazide treatment on the basis of conventional therapy.Comparison of the two groups of patients during clinical changes in blood pressure as well as the occurrence of adverse reactions.Results：After 4 weeks，blood pressure control in the experimental group were significantly better than the control group，the experimental group 2 patients had low blood pressure，control group，5 cases of hypotension and adverse reactions in patients in the experimental group were significantly lower than the control group（11.4 % vs27.3%）.Conclusion：For patients with refractory hypertension given irbesartan / hydrochlorothiazide the basis of conventional drug therapy in the treatment of the compound，can effectively control blood pressure，reduce the incidence of adverse reactions. 　　Key words irbesartan / hydrochlorothiazide tablets compound；resistant hypertension；clinical efficacy 　　高血压的发生与患者不良的生活习惯、心脑血管病变等因素有关，多见于超重、且长期缺乏锻炼的中老年人[1，2]。本次实验主要通过对我院近