复方丹参滴丸对慢性阻塞性肺疾病.docVIP

精品论文 参考文献 复方丹参滴丸对慢性阻塞性肺疾病 廖远芬 　　公安县合作医疗管理办公室湖北荆州434300 　　作者简介：廖远芬（196312），女，湖北荆州市人，本科学历，武汉医学院荆州分院，副主任医师。主要从事内科临床诊疗工作。 　　【摘要】 　　目的：探讨复方丹参滴丸对慢性阻塞性肺疾病（COPD）患者血液流变学的影响。方法：80例COPD患者随机分为治疗组和对照组（每组各40例），治疗组在常规治疗基础上加用复方丹参滴丸治疗；对照组进行常规治疗；疗程均为6月。检测并比较两组治疗前后的血液流变学指标。结果：两组在治疗后各项血液流变学指标均较治疗前降低，其中治疗组治疗后各项血液流变学指标降低明显优于对照组，差异有高度统计学意义（均P＜001）。结论：复方丹参滴丸对COPD患者的高血液黏度、血细胞高聚集性等血液流变学异常有明显改善作用。 　　【关键词】复方丹参滴丸；肺疾病，慢性，阻塞性；高黏滞血症；血液流变学 　　Compound danshen dropping pill for the influence of blood rheology in patients with chronic obstructive pulmonary disease 　　LIAO Yuanfang 　　【Abstract】Objective: To investigate the compound Danshen Dripping Pills on chronic obstructive pulmonary disease (COPD) patients with hemorheology. Methods: 80 patients with COPD were randomly divided into treatment group and control group (n = 40 cases), treatment group was added with Compound Danshen Dripping Pills in treatment on the basis of conventional therapy; the control group was given conventional treatment; treatment for June. Detection and blood rheology before and after treatment in the two groups of indices. Results: the two groups before and after treatment to reduce the hemorheological indices were observed before the treatment, the treatment group after treatment the hemorheological indices was significantly better than the control group, the difference was highly statistically significant (P ＜ 001). Conclusion: Compound Danshen Dripping Pills on COPD patients with high blood viscosity, blood cell aggregation and blood rheology abnormal improve. 　　【Key words】Compound Danshen dripping pills; pulmonary disease, chronic, obstructive; hyperviscosity syndrome; blood rheology 　　【中图分类号】R563 　　【文献标识码】B【文章编号】16748999(2013)12002602 　　慢性阻塞性肺疾病（COPD）患者普遍存在血液流变学异常，这是加重COPD患者肺损伤并发展成肺心病的重要原因之一［1］。复方丹参滴丸具备降低血小板聚集率、全血黏度、全血还原黏度、血小板黏附率并提高红细胞变形指数、红细胞电泳率、红细胞膜流动性等作用［2］，理应可以用于COPD血液流变学异常的治疗。本研究旨在探讨复方丹参滴丸对COPD患者血液流变学的影响，为临床治疗提供依据。 　　1对象与方法 　　11对象与分组： 选择2010年1月～2012年12月在本县某二甲医院门诊进行治疗的COPD患者。纳入标准：①临床诊断符合慢性阻塞性肺疾病诊治指南（2007年修订