复方丹参滴丸联合尼莫地平治疗慢性脑供血不足的疗效观察.docVIP

精品论文 参考文献 复方丹参滴丸联合尼莫地平治疗慢性脑供血不足的疗效观察 黄山秀(成都市成华区建设路社区卫生服务中心 四川成都 610051) 【中图分类号】R969 【文献标识码】A【文章编号】1672-5085（2013）16-0221-02 【摘要】 目的 观察复方丹参滴丸联合尼莫地平治疗慢性脑供血不足（CCCI）的疗效。方法 将86例CCCI患者按数字随机法分为两组。治疗组采用复方丹参滴丸10丸、尼莫地平40mg，口服，tid；对照组采用尼莫地平40mg，tid；均两周为一疗程。结果 总有效率治疗组(95.35﹪)优于对照组(76.74﹪)，P＜0.05；全血粘度、血浆比粘度等指标，治疗组比对照组低(P＜0.05)。结论 复方丹参滴丸联合尼莫地平治疗CCCI效果明显优于单用尼莫地平治疗，能明显改善CCCI患者脑动脉血液供应。 【关键词】 慢性脑供血不足 复方丹参滴丸 尼莫地平 Clinical Observation of Associated Application of Compound Danshen Dripping Pills and Nimodipine for Treating Chronic Cerebral Circulation Insufficiency 【Abstract】 Objective: To observe the clinical curative effect of associated application of compound danshen dripping pills and Nimodipine for treating chronic cerebral circulation insufficiency (CCCI). Methods: To divide 86 patients with CCCI into two groups randomly. One group which was named as treatment group, took 10 compound danshen dripping pills and Nimodipine 40 mg orally tid. While another group which was named as control group, took Nimodipine 40 mg orally tid. Both groups took 2 weeks to be a course of treatment. Results: The total effective rate of the treatment group (95.35%) was better than the control group (76.74%), Plt;0.05; eta;b, eta;s etc of the treatment group was lower than the control group (Plt;0.05). Conclusion: Associated application of compound danshen dripping pills and Nimodipine has much better curative effect than just Nimodipine for treating CCCI, and it can obviously improve the blood supply of cerebral arteries of patients with CCCI. 【Key Words】 chronic cerebral circulation insufficiency(CCCI); compound danshen dripping pills; Nimodipine 慢性脑供血不足(CCCI)是指各种原因导致大脑出现广泛的供血不足，引发脑部缺血、缺氧而出现一系列脑部功能障碍的临床表现的疾病，该病发病率高，据统计，中老年人有2/3的人患有此病，在脑梗塞和老年痴呆的发病前期大多曾长期有慢性脑供血不足的存在，如不及时治疗，易发生脑梗塞或痴呆，属中老年人的常见多发病，其主要症状是头晕、头痛、头重、失眠等，基础病因是高血压、高血脂和糖尿病；严重影响患者的生活质量。笔者对近两年在本中心就诊的CCCI患者应用复方丹参滴丸加尼莫地平口服治疗，取得了明显的疗效，现报告如下。 1 资料与方法 1.1 一般资料：本组病例86例，为2010年10月至2012年9月在我中心门诊就诊的CCCI病人，依数字表随机法分为两组，各4