老年原发性高血压合并静止性脑梗死患者颈动脉颅外段狭窄的临床研究.docVIP

老年原发性高血压合并静止性脑梗死患者颈动脉颅外段狭窄的临床研究 叠垫医院2007年3月第14卷第1,2期?21? ? l抱床研究? 老年原发性高血压合并静止性 脑梗死患者颈动脉颅外段狭窄的临床研究 林航.林敏 【摘要】目的:探讨老年原发性高血压静止性脑梗死与颈动脉颅外段狭窄的关系.方法::应用彩色多普勒超声 检查仅检测老年原发性高血压合并静止性脑梗死组(n=5o)和无静止性脑梗死组(n=114)患者的颈动脉颅外段血管管 腔直径,内膜一中层厚度,斑块及狭窄程度.结果:老年高血压合并静止性脑梗死组患者颈动脉颅外段狭窄的发生率及 粥样硬化斑块发生率分别为92.OO%和82.o0%,显着高于无静止性脑梗死组(64.91%和58.77%;P=0.0t)0和P= 0.0o4);不稳定斑块发生率为38.OO%.亦显着高于无静止性脑梗死组(7.o2%,P=0.000).与脑梗死病灶同侧的颈动 脉颅外段狭窄发生率为69.84%,显着高于非梗死侧(35.14%,P=0.001).结论:老年原发性高血压病合并静止性脑 梗死患者颈动脉颅外段狭窄和粥样硬化斑块.尤其是不稳定斑块有较高的发生率;颈动脉颅外段狭窄与颅内梗死病灶有 同侧相关性.对老年原发性高血压病患者定期进行颈动脉彩色多谱勒超声检查,及早期发现颈动脉颅外段狭窄并采取相 应措葱.对顶防缺血性脑血管病的发生有重要意义. 【关键词】静止性脑梗死;颈动脉狭窄;彩色多普勒超声;原发性高血压 CmlicaIStudyofExtramⅡ量alC删dArterialSten~Is InElderlyWlthEssentialHypenensi0nC锄pⅡ∞tedSilentCerebralInfal佃 LinH晶g,L-mMrm DepartmentofNeurology.NeumscienceCenter,Fuzl~uC-enendH~pita1.Fuzl~u350C25 【Abstract】Objective:Toinvestigatethe~rrelationbetweensilentcexebralinfarmion(SCI)ande~ranialcarodd8rte— rialst∞osi3(ECeAS)inelderlyWitlless∞thyperte~on.Method:Usilthe~lourl~pplerul~phytechnique,thelu— lllei1di~netex.intir~一mIiatNekne~.plaqueandtheextentof亡乜瑚malcarotidarterywerem∞suredatboththeirff~ction andt删ctiol1一freesidesinpad∞协withessentialhyperteIlsiol1inSCIgroup(n:5O),andeoml~redwithinwithoutSCI group(n:114).Ra豇llts;Theocc1lrrenceofECCASWaSgnif;candyhigherinSCIgroupthaninwithoutSCIgroup(92.00% ,,364.91%,P:0.ooO).Theoccu玎叽ceofcarotidplaque,especial】ytheunsteadyplaqueW舾highera3well(82.0t)%,,3 58.77%.38.0t)%,,37.02%,P=0.004.P:0.ooO).1-heoccurr明ceofEO^ASWaShigheratthe姗esideofstroke than∞n仕ahralartery(69.84%,,335.14%,P=0.o01).0咂d量on:ThereWaSahighoccurr∞ceofECCASandunsteady eamddplaqueintheelderlywithes!}entialhypertensioncomplicatedsilenteereb~liI1far戗ion.Thecaroddarteryultrasound臼c锄e shouldbecarriedontOtheelderlywithes3endalhypertensionreg1llarIyinordertofindoutECA2ASOne~xlys七age. 【Keyw戗_ds】Silentcerebralin~xction;Extraanjalca∞tid~-terMsten~is;ColorduplexIlltra∞r嘲;raphy;Essentialhy— pert目1si∞ 静止性脑梗死(silentcerebralinfarction,SCI)是指病 人未提供脑卒中病史或仅有轻微症状不足以引起患者和医 生的注意,而在CT或M