化疗药外渗致局部组织损伤后疼痛加重持续时间与转归的关系.docVIP

精品论文 参考文献 化疗药外渗致局部组织损伤后疼痛加重持续时间与转归的关系 黄女玲（广东省江门市新会区人民医院 广东新会 529100） 【中图分类号】R472.9 【文献标识码】A 【文章编号】1672-5085 (2010)33-0010-02 【摘要】 目的 研究静脉途径使用化疗药发生渗漏出血管外后，引起局部组织损伤后疼痛加重持续时间与转归的关系。方法 对发生化疗药外渗的74例患者，每天进行局部情况变化、疼痛持续时间、转归的观察，把局部表现红、肿、疼痛、转归良好的列为1组，把局部表现除有红、肿、疼痛外，还出现水泡、脱皮、溃疡等转归不良的列为2组，分析两组患者的疼痛加重持续时间的差异。结果 1组病例疼痛加重持续时间为1-5天，平均2.37plusmn;0.859 天，2组病例疼痛加重持续时间为4-9天，平均6.65plusmn;1.253 天。结论 化疗药外渗致局部组织损伤后疼痛加重持续时间越长，出现水泡、脱皮、溃疡等严重损伤的几率就越高。针对疼痛持续时间的不同，及早采取恰当的措施，以预防化疗药外渗致局部组织损伤后向不良转归发展，减轻患者的损伤，促进修复，并节约医疗资源，减轻患者负担。 【关键词】 化疗药 损伤 疼痛持续时间 转归 The relationship between the duration of pain and its outcome of local injury for extravasations of chemotherapeutic drugs 【Abstract】 Objective To study the relationship between the duration of pain and its outcome of local injury for extravasations of chemotherapeutic drugs by intravenous infusion. Methods The local conditions change, duration, prognosis of pain in every patient with extravasations of chemotherapeutic drugs were observed and recorded. Those with local red, swollen, pain and good outcomes were group 1; those with blisters, peeling, ulceration and poor outcomes, besides local red, swollen, pain, were group 2. The duration of pain in two groups were analyzed. Results The duration of pain in group 1 was 1~5d, average 2.37 plusmn; 0.859 d, the duration of pain in group 2 was 4~9d, average 6.65plusmn;1.253 d. Conclusions Longer is the duration of pain of local injury for extravasations of chemotherapeutic drugs, more likely serious injury like blisters, peeling, ulcer occurs. Appropriate measures should early take to prevent the local injury to adverse outcome according the different duration of pain, so as to reduce the injury of patients, promote restoration, and save the medical resources, reduce burden of patients. 【Key words】 Chemotherapeutic drugs Injury Duration of pain Outcome 化疗药在静脉注射或静脉滴注过程中，如渗漏出血管外，早期可引起局部组织发生红、肿、疼痛等炎症反应，部分病例之后可出现水泡、脱皮、溃疡等，有的还有肢体水肿、功能障碍，难以继续化疗。因此，正确判断化疗药外渗致局部组织损伤后的发骨魇疲笆辈扇ang;嘤Phi;脑し