安宫牛黄丸加减治疗脑出血急性期脑损伤的临床研究.docVIP

精品论文 参考文献 安宫牛黄丸加减治疗脑出血急性期脑损伤的临床研究 莫云芳 　　（重庆市九龙坡区第一人民医院 重庆 400050） 　　【摘要】 目的：探讨安宫牛黄丸加减治疗脑出血急性期脑损伤的临床效果。方法：将脑出血急性期脑损伤患者84例随机分为两组，对照组42例行常规治疗，观察组42例联用安宫牛黄丸加减治疗，比较两组治疗效果。结果：治疗后，两组血浆脑钠肽、格拉斯哥昏迷评分均显著增加（P＜0.05），神经功能缺损评分均显著降低（P＜0.05）。观察组血浆脑钠肽、格拉斯哥昏迷评分、格拉斯哥预后评分、治疗总有效率均明显高于对照组（P＜0.05），神经功能缺损评分明显低于对照组（P＜0.05）。结论：安宫牛黄丸加减治疗脑出血急性期脑损伤的疗效显著，可明显改善患者预后。 　　【关键词】 安宫牛黄丸加减；脑出血；急性期脑损伤 　　【中图分类号】R242 【文献标识码】B 【文章编号】2095-1752（2016）06-0346-02 　　Clinical research of Angong Niuhuang pill in treatment of cerebral hemorrhage in acute stage of brain injury Mo Yunfang. 　　First peoples Hospital, Jiulongpo, 400050,China 　　【Abstract】Objective To investigate effect of Angong Niuhuang pill in treatment of cerebral hemorrhage in acute stage of brain injury. Methods 84 patients with cerebral hemorrhage in acute stage of brain injury were randomly divided into two groups. 42 patients received conventional treatment as control group. 42 patients combined with Angong Niuhuang pill as observation group. Treatment effect was compared between two groups. Results After treatment, plasma BNP, GCS score significantly increased(Plt;0.05) while neurological function defect score significantly decreased(Plt;0.05) in two groups. Plasma BNP, GCS score, GOS score, total effective rate in observation group were significantly higher than control group (Plt;0.05). Neurological function defect score in observation group was significantly lower than control group (Plt;0.05). Conclusion Angong Niuhuang pill has significant effect in treatment of cerebral hemorrhage in acute stage of brain injury, which can significantly improve prognosis of patients. 　　【Key words】Angong Niuhuang pill; Cerebral hemorrhage; Acute stage of brain injury 　　脑出血是临床常见病症，高发于老年高血压患者[1]，具有致残率高、致死率高的特点。急性期脑损伤是脑出血诱发的危重症，可继发脑缺血、脑水肿、脑疝而危及患者生命，目前尚无标准的治疗方法。中医认为[2]，安宫牛黄丸具有化瘀、醒脑开窍、行气通络的功效，可用于急性脑血管病的治疗，能改善脑部微循环，并保护脑细胞。此次研究对42例脑出血急性期脑损伤患者行常规治疗联合安宫牛黄丸加减治疗，疗效显著，现报道如下。 　　1.临床资料 　　1.1 一般资料 　　2011年12月至2014年10月脑出血急性期脑损伤患者84例，