礞石滚痰丸加减方对痰热内扰型失眠症生活质量影响研究Mengshi guntan Pill on life quality effect of phlegm heat type insomnia.pdfVIP

提 要 目的：观察礞石滚痰丸加减方治疗痰热内扰型失眠症患者生活质量的影响，以期 为失眠症的辨证治疗提供新的思路和有效方药。 方法：将 80 例痰热内扰型失眠症患者随机分为礞石滚痰丸加减方治疗组和舒眠 胶囊对照组，治疗 28 天。观察治疗前后失眠程度改善情况，以及匹兹堡睡眠质量指 数量表（PSQI）各因子分及总分、世界卫生组织生活质量简表（WHOQOL-BREF）计分 的变化。 结果：经统计学分析，治疗组总有效率 87.5％，对照组总有效率 77.5％，两组 比较总有效率有显著性差异（P＜0.05）。治疗组与对照组对失眠程度分级计分均有改 善作用（P＜0.01，P＜0.05），治疗组优于对照组（P＜0.05）。两组比较总有效率有 显著性差异（P＜0.05）。治疗组与对照组对 PSQI 评分均有改善作用（P＜0.01），治 疗组在入睡时间、睡眠效率、日间功能因子分和总分优于对照组（P＜0.05）。治疗组 和对照组 QOL 计分改善在生理领域、心理领域和社会关系领域有显著性差异（P＜ 0.05），在环境领域无显著性差异（P＞0.05）。 结论：礞石滚痰丸加减方可以有效缓解失眠，改善患者生活质量。 关键词 礞石滚痰丸加减方；痰热内扰；失眠症；生活质量 The Effects of Mengshiguntan Pill Jiajian Fang on Improving Quality of Life of Insomnia Speciality: Internal Medicine of TCM Author: Yin Gaoyun Tutor: Chief Physician Hu Zhiqiang Abstract Object: To observe the effect of Mengshiguntan Pill Jiajian Fang on the quality of life of patients suffering from insomnia，so as to find new ideas and effective prescriptions. Methods ：80 patients with insomnia were randomly divided into the treatment group （Mengshiguntan Pill Jiajian Fang-group n=30 ）and control group （Shumian capsules-group n=30 ）.Both were treated for 28 days, and then being compared with their improvement of insomnia degree and the scores of Pittsburgh Sleep Quality Index （PSQI ）， WHOQOL-BREF before and after treatment. Results:The statistic analysis revealed that Mengshiguntan Pill Jiajian Fang is safe and effective.The total effective rate is 87.5% ；while the control group is 77.5%.There was significant difference between them （P ＜0.05 ）.The insomnia degree in both the treatment group and the control group was improved （P ＜0.01，P ＜0.05 ）,but the former are superior to the later （P ＜0.05 ）. The Mengshiguntan Pill Jiajian Fang decreased