复方丹参滴丸治疗老年心衰患者后血浆pro-BNP表达变化研究.docVIP

复方丹参滴丸治疗老年心衰患者后血浆pro-BNP表达变化研究 王宁勃 田刚 雷华斌 魏铁军 郭艺静 西安交通大学医学院第一附属医院心血管内科 铜川市人民医院南院心血管内科 北京中医药大学第七临床医院内科 铜川市人民医院南院消化内科 铜川市人民医院南院内分泌科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的:探讨复方丹参滴丸治疗老年心力衰竭 (心衰) 的临床疗效及对患者血浆B型利钠肽前体 (proBNP) 水平的影响。方法:将92例老年心衰患者随机分成对照组与观察组, 每组46例。其中对照组给予常规西医治疗, 观察组在对照组的基础上加用复方丹参滴丸10粒/次, 3次/天, 2组疗程均为6个月。观察并记录2组患者治疗前及治疗1、3、6个月后血浆pro-BNP水平变化情况, 治疗6个月后的临床疗效及治疗期间不良反应的发生情况。结果:对照组治疗6个月后的血浆pro-BNP水平显著低于治疗前, 差异有统计学意义;观察组治疗3、6个月后的血浆pro-BNP水平均显著低于治疗前, 同时也显著低于对照组, 差异有统计学意义;治疗6个月后观察组的临床疗为91.3%效显著优于对照组76.1%, 差异有统计学意义。结论:复方丹参滴丸治疗老年心衰能够有效降低患者的血浆pro-BNP水平, 且疗效显著, 安全可靠。 关键词： 复方丹参滴丸; 老年心衰; B型利钠肽前体; 作者简介：田刚, E-mail:1049741773@。 收稿日期：2017-09-01 Clinical effect of compound Danshen dropping pills for the elderly patients with heart failure and its influence on the plasma pro-BNP Wang Ning-bo Tian Gang Lei Hua-bin Wei Tie-jun Guo Yi-an Internal Medicine-Cardiovascular Department The First Affiliated Hospital of Xian JiaoTong University Medical College; Internal medicine The seventh Clinical Hospital of Beijing University of Chinese Medicine; GI Medicine Tongchuan Peoples Hospital; Endocrine Department Tongchuan Peoples Hospital; Abstract： Objective To investigate the clinical effect of compound Danshen dropping pills therapy in patients with congestive hearts failure, and to analysis its effect on the plasma pro-BNP. Methods Ninety-two patients with congestive hearts failure were randoly divided into control group and observation group, each group 46 cases. The control group were treatment by routine western medicine, and the observation group were treatment by compound Danshen dropping pills 10 pills one time, 3 times one day, one course of the treatment of each group is six months. Then observed and recorded the level of the plasma proBNP before and one, three, six months after treatment, the clinical effect and the adverse reaction. Results In the control group, six months after treatment, the level of the plasma pro-BNP