妇炎消胶囊联合西药治疗急性盆腔炎临床疗效及对患者血液流变学的影响.docVIP

妇炎消胶囊联合西药治疗急性盆腔炎临床疗效及对患者血液流变学的影响 童蓉 刘玉嵚 邢艳霞 青海省交通医院妇产科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的:探讨妇炎消胶囊联合西药治疗急性盆腔炎临床疗效及对患者血液流变学、炎性反应指标水平的影响。方法:选取2012年6月至2016年12月青海省交通医院确诊急性盆腔炎且中医证型属湿热内蕴型的患者89例, 随机分为对照组和观察组, 对照组45例采用左氧氟沙星及替硝唑静滴抗感染, 观察组44例联合妇炎消胶囊口服, 7 d为1个疗程。比较治疗前后症状积分、血液流变学及超敏C反应蛋白 (hs-CRP) 、肿瘤坏死因子 (TNF-a) 、白介素-2 (IL-2) 等指标改善情况, 比较2组临床疗效及生命质量情况。结果:治疗后, 患者下腹痛、带下增多、经量多等症状积分降低, 差异有统计学意义 (P0.05) ;患者血液流变学 (低切血黏度、高切血黏度、血浆黏度) 及炎性反应指标 (TNF-a、hs-CRP) 水平降低, IL-2则较前升高, 但观察组均改善更显著 (P0.05) ;治疗后, 患者生命质量量表中躯体功能、情绪功能、心理功能、社会功能等维度均升高, 但观察组水平更高 (P0.05) ;对照组总有效率75.56% (34/45) , 观察组为93.18% (41/44) , 明显高于对照组 (P0.05) 。结论:妇炎消胶囊联合西药治疗急性盆腔炎疗效显著, 可更好地改善临床症状, 抑制炎性反应渗出, 纠正血液高凝状态, 优于单用西医抗感染干预, 值得推广。 关键词： 妇炎消胶囊; 急性盆腔炎; 血液流变学; 炎性反应因子; 作者简介：童蓉 (1979.04—) , 女, 本科, 主治医师, 研究方向:妇产科疾病的治疗, E-mail:545231017@ 收稿日期：2017-05-17 基金：青海省科技厅应用基础研究计划项目 (2013-Z-739) Clinical Efficacy of Fuyanxiao Capsule Combined with Western Medicine in Treating Acute Pelvic Inflammatory and Effects on Patients Hemorheology Tong Rong Liu Yuqin Xing Yanxia Department of Obstetrics and Gynecology, Qinghai Jiaotong Hospital; Abstract： Objective: To investigate the clinical curative effects of Fuyanxiao capsule combined with western medicine in treating acute pelvic inflammatory and effects on hemorheology and inflammatory indexes. Methods: A total of 89 cases with acute pelvic inflammatory disease of dampness heat syndrome, who were diagnosed in Qinghai Jiaotong Hospital from June 2012 to December2016, were randomly divided into control group ( 45 cases) and observation group ( 50 cases) . The control group was treated with levofloxacin and Tinidazole intravenous against infection, and the observation group was treated combined with Fuyanxiao capsules orally, with 7 d as a treatment course. The symptom scores, hemorheology, high sensitivity C reactive protein ( hs-CRP) , tumor necrosis factor ( TNF-a) and interleukin-2 ( IL-2) and other indicators before and after treatment were