舒尼替尼联合多西他赛序贯给药作用于EGFR-TKIs抵抗的非小细胞肺癌协同机制的研究Study of the synergistic mechanism of suninib combined with docetaxel in non small cell lung cancer with EGFR-TKIs resistance.pdfVIP
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舒尼替尼联合多西他赛序贯给药作用于EGFR-TKIs抵抗的非小细胞肺癌协同机制的研究Study of the synergistic mechanism of suninib combined with docetaxel in non small cell lung cancer with EGFR-TKIs resistance
目 录
英文缩略词表1
中文摘要2
英文摘要4
正文7
2 材料与方法10
3 结果21
4 讨论32
5 结论35
参考文献36
附录43
致谢46
综述47
英文缩略词表
Abbreviation
英文缩写 英文全称 中文全称
CI combination index 联合指数
c-kit stem cell factor receptor 干细胞生长因子受体
DMSO dimethyl sulfoxide 二甲基亚砜
epidermal growth factor receptor 表皮生长因子受体酪氨酸激
EGFR-TKIs
tyrosine kinase inhibitors 酶抑制剂
FDA food and Drug Admistraton 美国食品药品管理局
Fig figure 图
HR hazard ratio 风险比
IC50 half maximal inhibitory concentration 半数抑制浓度
MTT methyl thiazolyl tetrazolium 甲基噻唑基四唑
NSCLC non–small cell lung cancer 非小细胞肺癌
ORR objective response rates 客观反应率
OS overall survival 总生存
P probability 概率
PBS phosphate buffer saline 磷酸缓冲液
PDGF platelet-derived growth factor 血小板源性生长因子
PDGFR platelet-derived growth factor receptor 血小板源性生长因子受体
PFS progression-free survival 无进展生存
glial cell-line-derived neurotrophic 胶质细胞源性神经营养因子
RET
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