泮托拉唑、立止血联合奥曲肽唑治疗上消化道出血的回顾性临床分析.docVIP

精品论文 参考文献 泮托拉唑、立止血联合奥曲肽唑治疗上消化道出血的回顾性临床分析 武汉市黄陂区六指中心卫生院甘棠分院 湖北武汉 430300 摘要：目的：探讨泮托拉唑、立止血联合奥曲肽治疗急性上消化道出血的临床疗效及安全性.方法：回顾性分析我院2015年8月-2016年9月住院的急性上消化道出血病例72例，患者随机分两组，对照组用泮托拉唑、立止血治疗，观察组用泮托拉唑、立止血联合奥曲肽治疗，治疗1w后，比较疗效。结果：治疗组总有效率 97.23%，对照组总有效率86.11% 两组比较有显著差异（Plt;0.05）。结论：泮托拉唑、立止血联合奥曲肽治疗上消化道出血疗效显著，且无明显的不良反应，三种药物联用效果最好。 关键词：泮托拉唑；立止血；奥曲肽；急性上消化出血 [Abstract] Objective：to discussion of pantoprazole，hemostasis in combination with octreotide in the treatment of acute upper digestive tract hemorrhage clinical efficacy and safety. Methods：a retrospective analysis of our hospital in August 2015 - 2016 September of acute upper gastrointestinal bleeding were 72 cases. The patients were randomly divided into two groups，the control group was treated with pantoprazole，Reptilase in treating，the observation group with pantoprazole，hemostasis in combination with octreotide treatment，treatment after 1W and compare the efficacy. Results：the total effective rate of the treatment group was 97.23%，and the total effective rate of the control group was 86.11% and there was significant difference between the two groups（Plt;0.05）. Conclusion：pantoprazole，hemostasis in combination with octreotide in the treatment of upper digestive tract hemorrhage curative effect is distinct，and no obvious adverse reactions，three drug combination has the best effect. [keyword] pantoprazole；Reptilase；octreotide；acute upper gastrointestinal hemorrhage 消化道出血是临床常见的严重症候。消化道是指从食管到肛门的管道，包括胃、十二脂肠、空肠、回肠、盲肠、结肠及直肠。上消化道出血部位指屈氏韧带以上的食管、胃、十二指肠、上段空肠以及胰管和胆管的出血。而在临床实践中，上消化道大出血是极为常见的严重病症，如果治疗不及时或者治疗方法不妥当的话，则会很容易造成死亡。因此，明确患者上消化道出血的原因，及时、准确、恰当的治疗及护理，对其病情的控制及预后有重要的意义［1］。近年来，我们采用泮托拉唑、立止血联合奥曲肽治疗上消化道出血72例，获得了满意的疗效，现报道如下。 1.1 临床资料 选择2015年8月-2016年9月我院收治的72例急性上消化道出血上消化道出血患者，其中男41例，女31例，年龄22-64岁，平均（42.7+11.5）岁，其中胃黏膜病变15例，消化道溃疡21例，胃底静脉曲张破裂17例，胃癌12例，食管裂孔疝7例。依据随机数字表将患者分为A组和B组，A组：36组，男21例，女l5例，平均（45.61plusmn;12.3）岁，胃黏膜病变8例，消化道溃疡l1例，胃底静脉曲张破裂9例，胃癌6例，食管裂孔疝3例；B组：36例，男20例，女16例，平均年龄（38.7plusmn;9.5）岁，胃黏膜病变7例，消化道溃疡10例，胃底静脉曲张破裂9