特发性肺纤维化合并肺癌的临床分析.docVIP

精品论文 参考文献 特发性肺纤维化合并肺癌的临床分析 周维华 江苏省海安县人民医院呼吸内科 226600 　　摘要：目的 对特发性肺纤维化合并肺癌的临床治疗情况进行观察分析。方法 选取于我院2010年1月～2015年7月接受治疗的18例特发性肺纤维化合并肺癌患者作为观察对象，对其临床资料及治疗情况进行分析。结果 特发性肺纤维化合并肺癌患者的高危因素包括粉尘吸入、吸烟、男性及暴露等，肺功能表现出限制性通气功能障碍及不同程度的弥散功能障碍，6例患者由于病情严重无法耐受肺功能检查。肺下叶及外周多见肿瘤，以鳞状细胞癌为主要病理类型。结论 特发性肺纤维化患者在治疗过程中应警惕肺癌的同时发生，应采取胸部CT及血清CEA对患者进行监测，由于特发性肺纤维化患者肺功能存在不同程度的损伤，使得化疗治疗存在限制，同时抗癌药物及放疗容易引起肺纤维化的加快并产生副作用，因此，特发性肺纤维化合并肺癌的预后效果不佳，还需进一步研究。 　　关键词：特发性肺纤维化；肺癌；临床分析 　　Idiopathic pulmonary fibrosis, combined the clinical analysis of lung cancer Zhou Weihua ,Haian county of jiangsu province peoples hospital of respiratory medicine,Haian, jiangsu province, 226600 　　Abstract: Objective Idiopathic pulmonary fibrosis with lung cancer clinical treatment were observed and analyzed. Methods In our hospital in January 2010 ~ July 2015 treated 18 cases of idiopathic pulmonary fibrosis in patients with lung cancer as an object of observation, clinical data and treatment were analyzed. Results Idiopathic pulmonary fibrosis patients with lung cancer risk factors include dust inhalation, smoking, and other men and exposure, lung function showed a restrictive ventilatory dysfunction and varying degrees of diffusion dysfunction, six cases of patients due to serious illness can not be tolerated pulmonary function tests. Lower lobe and peripheral common tumors, squamous cell carcinoma as the main pathological type. Conclusion Special idiopathic pulmonary fibrosis patients during treatment should be alert to the occurrence of lung cancer at the same time, should take chest CT and serum CEA patient monitoring, since lung function in patients with idiopathic pulmonary fibrosis varying degrees of damage, so chemotherapy treatment there is a limit, while anti-cancer drugs and radiation likely to cause pulmonary fibrosis accelerate and cause side effects, therefore, poor idiopathic pulmonary fibrosis lung cancer prognosis merger, needs further study. 　　Keywords: idiopathic pulmonary fibrosis; lung cancer; clinical analysis