痰热清注射液治疗儿童腺病毒肺炎疗效观察.docVIP

精品论文 参考文献 痰热清注射液治疗儿童腺病毒肺炎疗效观察 济宁医学院附属济宁市第一人民医院儿科 272013 摘要：目的　观察痰热清注射液治疗儿童腺病毒肺炎的临床效果。方法168例腺病毒肺炎患儿随机分为研究组和对照组，每组 84例。研究组给予痰热清注射液联合抗病毒及止咳化痰等药物治疗；对照组：仅给予抗病毒及止咳化痰药物，比较两组治疗效果、症状及体征变化及毒副作用。结果：治疗前后临床症状、体征改善情况具有明显差异，研究组症状、体征消失短于对照组（Plt;0.05）；显效率、总有效率分别为79.76%和97.62%　明显高于对照组63.10%和91.67%，两组比较有显著性差异（Plt;0.05）。结论：痰热清注射液辅助抗病毒药物等治疗腺病毒肺炎疗效确切、无明显毒副作用，值得临床推广应用。 关键词：　痰热清注射液 治疗 腺病毒肺炎 儿童 ABSTRACT：[Objective]To evaluate the efficacy of Tanreqing injection in the treatment of children adenovirus pneumonia.[Methods]168 cases of children adenovirus pneumonia were divided into two groups randomly：Study group and control group，84 cases in each group.Study group were given Tanreqing and medicines of antivirals and relieving cough and phlegm，while the treated group was added with only medicines of antivirals and relieving cough and phlegm.The clinical effect and the improved symptom were evaluated，and the adverse reaction was observed.Results：The clinical effect and the improved symptom have significant difference between the two groups，the study group was significantly shorter than the comtrol group（Plt;0.05）；In study group，the total effective rate and excellence was 79.76%and 97.62%，significantly higher than that of the control group 63.10%and 91.67%，which have significant difference（P＜0.05）.Conclusion：The combination of Tanreqing and medicines of antivirals and relieving cough and phlegm has a good effect in treating children adenovirus pneumonia，and it is worth of clinical application. Key words：Tanreqing injection，treatment，adenovirus pneumonia，children 腺病毒（ADV）是引起小儿急性呼吸道感染的重要病原，其中引起肺炎的占4%-10%，而重症肺炎的占19.3%，是小儿时期最严重的肺炎之一，病情重、并发症多、病死率高、易留有各种后遗症等特点［1］，对其治疗相当棘手与困难。本文采用了痰热清辅助抗病毒等药物对年龄在2岁以上的腺病毒肺炎患儿进行了治疗并取得了良好的临床效果，总结报告如下。 1　资料与方法 1.1　临床资料　选择本院 2014年3月 至2016 年 3 月收治的年龄2岁以上的腺病毒肺炎患儿 168 例，符合《褚福棠实用儿科学》第七版中关于儿童腺病毒肺炎的诊断标准［2］，其中 男 97 例，女71例，年龄 2～12 岁，平均年龄 5.5plusmn;3.2 岁；病程3～5天（d）内者通过呼吸道咽试子腺病毒抗原免疫荧光检测，病程超过5d以上者采血检测腺病毒免疫荧光抗体，检测结果为阳性时才确诊为入选病例，病程为 2～10d，平均病程 5.2plusm