腰椎峡部裂病理模型的建立和疲劳特性的研究.docVIP

精品论文 参考文献 腰椎峡部裂病理模型的建立和疲劳特性的研究 张志 王簕 吕玉明 张亮 曾勉东（广州医学院第三附属医院骨科 510150） 【中图分类号】R683【文献标识码】A【文章编号】1672-5085（2011）46-0112-03 【摘要】目的 对比分析腰椎峡部内、外部分骨质的抗疲劳特性。方法 12例成人新鲜腰L5椎标本模型，随机分为两组，每组6例，分别用咬骨钳咬除腰椎峡部外1/2或内1/2骨质，制作腰椎峡部外1/2缺损和内1/2缺损病理模型。采用游标卡尺对剩余腰椎峡部的宽度进行测量。对腰椎峡部外1/2缺损模型与腰椎峡部内1/2缺损模型的峡部缺损后宽度进行统计对比。将标本固定于脊柱三维运动试验机上，依次将腰椎峡部外1/2缺损和内1/2缺损病理模型标本置于生物材料力学试验机上，分别给予压缩负荷。记录断裂次数进行统计学分析。结果 正常L5左侧腰椎峡部宽度为15.06plusmn;0.83,正常右侧腰椎峡部宽度为14.85plusmn;0.72, 左右侧对比P=0.52。腰椎峡部外1/2缺损模型峡部宽度为5.24plusmn;0.41,腰椎峡部内1/2缺损模型峡部宽度为5.15plusmn;0.34, 对比P=0.57。腰椎峡部外1/2缺损模型峡部断裂次数为25160plusmn;1019，腰椎峡部内1/2缺损模型峡部断裂次数为18782plusmn;3126，对比P=0.006。结论 腰椎峡部外1/2缺损模型抗疲劳性优于腰椎峡部内1/2缺损模型，腰椎峡部内1/2承担了更多的腰椎负荷应力。同一应力下，腰椎峡部外1/2更容易疲劳骨折。 【关键词】腰椎峡部 生物力学 A Study on Fatigue characteristics of lumbar spondylolysis and stress distribution of conduction Zhang Zhi, Wang Le, Lv Yuming, Zhang Liang, Zengmingdong, (the third Affiliated Hospital of Guangzhou Medical College, GuangZhou 510150) 【Abstract】Objective: To make pathologic defect models of isthmus external 1/2 and internal 1/2, To compare and analyze the anti-fatigue features of these two models.Methods: Take 12 fresh lumbar vertebra specimens. Divide these 12 specimens randomly into 2 groups. Use rongeur to remove respectively the external 1/2 isthmus and the internal 1/2 isthmus bone and then make pathological defect models. Use electric vernier caliper to measure the width of the remaining isthmus. Compare the width of the external 1/2 isthmus defect model and the internal 1/2 isthmus defect model. Fix the specimen on spine 3D movement test machine, put the external 1/2 isthmus defect model and the internal 1/2 isthmus defect model on mechanic test machine. Record the breakage times and analyze them. Result: The width of the normal L5 left isthmus portion of lumbar vertebra is 15.06 plusmn;0.83, the right width is 14.85 plusmn;0.72. The difference between the left width and the right width is P=0.52. The isthmus width of the external 1/2 isthmus defect model is 5.24 plusm