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11381138 Suxamethonium Chloride Injection / O‹cial Monographs JP XV tion of ammonium acetate (1 in 100), acetone, 1-butanol and tralization with 0.1 mol L sodium hydroxide VS in the As- W formic acid (20:20:20:1) to a distance of about 10 cm, and say: not more than 0.7 mL of 0.1 mol L sodium hydroxide W dry the plate at 1059C for 15 minutes. Spray evenly platinic VS is required for each 200 mg of Suxamethonium Chloride chloride-potassium iodide TS on the plate: the spots obtained (C H Cl N O ) taken. 14 30 2 2 4 from the sample solution and standard solution are blue-pur- Extractable volume 6.05 It meets the requiremeut. ple in color and have similar R f. Assay Transfer to a separator an accurately measured pH 2.54 The pH of a solution of Suxamethonium Chlo- volume of Suxamethonium Chloride Injection, equivalent to ride for Injection (1 in 100) is between 4.0 and 5.0. about 0.2 g of suxamethonium chloride (C H Cl N O ), 14 30 2 2 4 Purity Related substances—Take an amount of Sux- add 30 mL of freshly boiled and cooled water, and wash the amethonium