艾司西酞普兰与帕罗西汀治疗强迫症的临床分析.docVIP

精品论文 参考文献 艾司西酞普兰与帕罗西汀治疗强迫症的临床分析 赵献民 　　（河南省濮阳市精神卫生中心 河南濮阳 457000） 　　【摘要】目的：探讨强迫症采用艾司西酞普兰与帕罗西汀治疗的临床效果。方法：回顾性分析2013年8月～2015年8月本院收治的124例强迫症患者的一般资料，所有患者均经临床检查确诊，并自愿签署知情同意书。将其按照随机数字表法分为实验组（艾司西酞普兰）与对照组（帕罗西汀）。采用耶鲁布朗强迫症状量表（Y-BOCS）分析两组患者的临床治疗疗效。结果：实验组患者临床治疗总有效率高于对照组（P﹤0.05）；治疗前，两组患者Y-BOCS评分无显著性差异（P﹥0.05）；治疗后4周、8周，两组患者的Y-BOCS评分明显改善，但实验组优于对照组（P﹤0.05）。结论：艾司西酞普兰在强迫症治疗中有着较帕罗西汀更为显著的效果，且起效时间快，值得进行深入研究和推广。 　　【关键词】强迫症；艾司西酞普兰；帕罗西汀 　　【中图分类号】R453 【文献标识码】A 【文章编号】1007-8231（2016）02-0059-02 　　 Clinical analysis of Ai Sciplan and Pa Rossi Dean in the treatment of obsessive compulsive disorder 　　 Zhao Xianmin. The mental health center of Puyang City, Henan Province,Puyang Henan 457000 　　【Abstract】Objective To investigate the clinical effect of Ai Sciplan and Pa Rossi Dean with obsessive-compulsive disorder treatment. Methods A retrospective analysis of general data of 124 patients with OCD patients in August 2013～2015 year in August in our hospital, all patients were diagnosed by clinical examination, and signed informed consent voluntarily. They were randomly divided into experimental group and control group (Ai Sciplan) (Pa Rossi Dean). Clinical therapeutic effect of two groups of patients were analyzed by Yale Brown Obsessive Compulsive Scale (Y-BOCS). Results The clinical treatment of patients in the experimental group the total efficiency is higher than that of the control group (P lt; 0.05); before the treatment, the Y-BOCS scores in the two groups no significant difference (P gt; 0.05); 4 and 8 weeks after treatment, Y-BOCS score of two groups of patients improved obviously, but the group is better than control group (P lt; 0.05). Conclusion Escitalopram in the treatment of obsessive-compulsive disorder (OCD) has a more significant effect than that of paroxetine and onset time soon, it is worth in-depth study and promotion. 　　【Key words】Ai Sciplan obsessive-compulsive disorder; Paroxetine 　　强迫症在临床上较为常见，发病率较高。根据相关调查研究显示，强迫症终身发病率约为1%～3%[1]。该