血栓抽吸联合替罗非班在急性心肌梗死急诊介入治疗中的疗效观察.docVIP

精品论文 参考文献 血栓抽吸联合替罗非班在急性心肌梗死急诊介入治疗中的疗效观察 石磊 白宏 索郢 安超 　　（内蒙古乌海市人民医院心内科 内蒙古 乌海 016000） 　　【摘要】 目的：评价血栓抽吸导管联合替罗非班在急性ST段抬高心肌梗死（STEMI）介入术中应用疗效。方法：选择2012年3月至2014年10月行急诊冠状动脉介入治疗（PCI）的急性ST段抬高心肌梗死患者86例，其中应用抽吸导管和替罗非班后行PCI组46例，常规PCI对照组40例。观察2组的造影结果、术后效果及安全性。结果：研究组发病距血管再通时间、术后2小时ST段回落gt;50%和心肌酶学峰值时间均优于对照组（均Plt;0.05）；梗死相关血管（IRA）无复流发生率明显低于对照组（Plt;0.05），左室射血分数（LVEF）及左室舒张末内径（LVEDd）明显好于对照组，住院期间主要不良心血管事件（MACE，包括死亡、再梗死、再次靶血管重建）的发生率少于对照组，差异有统计学意义（P均lt;0.05）。结论：血栓抽吸联合替罗非班治疗急性ST段抬高心肌梗死可减少无复流或慢血流发生，可改善术后心脏功能，并且不增加血管不良事件的发生率。 　　【关键词】 急性ST段抬高心肌梗死；冠状动脉介入治疗；血栓抽吸导管；替罗非班 　　【中图分类号】R453 【文献标识码】A 【文章编号】2095-1752（2015）26-0140-02 　　Effect of thrombus aspiration combined with tirofiban during urgent percutaneous coronary intervention in patients with acute myocardial infarction Shi Lei,Bai Hong,Suo Ying,AN Chao. (Peoplersquo;s Hospital, Wuhai 016000, NeiMonggol, China) 　　【Abstract】 Objective To evaluate the effect of thrombus aspiration combined with Tirofiban During urgent percutaneous coronary intervention(PCI) in patients with acute myocardial infarction(AMI). Methods A total of 86 AMI patients with urgent PCI were enrolled from March 2012 to October 2014. There were 46 patients received PCI and suck by catheter combined with Tirofiban, another 40 patients received routine PCI. Observe the two groups of angiography, postoperatine efficacy, and safety. Results There was lower peak serum CK-MB, TNI in the study group, compared with the control group, ratio of ST segment resolutiongt;50% and the coronary artery recanalization time was significantly better (Plt;0.05), no-refiow in Infarct-related Artery(IRA) after PCI was lower than the control group (Plt;0.05), left ventricular diastolic diameter(LVEDd), left ventricular ejection fraction(LVEF) and MACE rates in stady group were superior to those in the control group (Plt;0.05). Conclusion Application of suck by catheter combined with tirofiban in patients with acute myocardial infarction was effectiv