血液高凝状态与活动性UC病情分级、转归的相关性研究.docVIP

精品论文 参考文献 血液高凝状态与活动性UC病情分级、转归的相关性研究 岳阳县人民医院 湖南岳阳 414100 【摘 要】目的 探讨血液高凝状态与活动性溃疡性结肠炎（UC）病情分级、转归的相关性。方法 收集2013 年1 月至2015 年10 月我院收治的活动性UC患者66 例，同时选取同期来我院接受健康体检的体检者20 例，比较不同严重程度UC患者和健康体检者血D-二聚体水平，同时将66 例活动性UC 患者随机平分为两组，对照组（n=33）接受常规UC治疗，观察组（n=33）在接受常规UC治疗之前，先进行抗凝治疗，比较两组患者治疗前后血D-二聚体水平和UC治疗效果。结果 UC重度活动组患者的血D-二聚体水平为521.32plusmn;57.49 mg/L；中度活动组患者为357.94plusmn;49.88 mg/L；轻度活动组患者为226.05plusmn;41.94 mg/L；健康体检组为148.39plusmn;55.39 mg/L，组间差异具有统计学意义，Plt;0.05；观察组患者治疗??血D-二聚体水平为212.94plusmn;60.76 mg/L，对照组为275.93plusmn;56.83 mg/L，Plt;0.05；观察组患者治疗有效率为87.88 %，对照组为69.70 %，Plt;0.05。结论 血液的高凝状态与活动性UC病情严重程度呈正相关，控制UC患者的血液高凝状态，对于提高患者的治疗效果具有积极作用，值得推广应用。 【关键词】血液；高凝状态；活动性；溃疡性结肠炎；病情分级；转归 【Abstract 】 objective to investigate the blood coagulation state and high active ulcerative colitis（UC）classification conditions，and the outcome of the correlation. Collected from January 2013 to October 2015，our hospital 66 cases of patients with active UC，and at the same time to the hospital to accept physical examination examination of 20 cases，and comparison of different severity in patients with UC and healthy check-up blood D - dimer level，at the same time will be 66 active UC patients randomly divided into two groups，control group（n = 33）treated with conventional UC，observation group（n = 33）before accepting routine UC treatment to anticoagulation，compared two groups of patients before and after treatment the blood D - dimer level and UC treatment. Results blood group of patients with severe UC activity D - dimer level was 521.32 + / - 57.49 mg/L；Patients with moderate activity group was 357.94 + / - 49.88 mg/L；Mild activity groups of patients was 226.05 + / - 41.94 mg/L；Health TiJianZu was 148.39 + / - 55.39 mg/L，statistically significant differences between groups，P lt; 0.05；Observation group of patients after treatment the blood D - dimer level was 212.94 + / - 60.76 mg/L，275.93 + / - 56.83 mg/L，the control group（P lt; 0.05；Observation group of patients treatment effective rat