血浆胆红素吸附在高胆红素血症治疗中的应用.docVIP

精品论文 参考文献 血浆胆红素吸附在高胆红素血症治疗中的应用 1：天津中医药大学 天津 300000 2：天津武清中医医院 天津 300000 3：天津市第一中心医院 301700 【摘要】目的 探讨血浆胆红素吸附在高胆红素血症中治疗效果。方法 选取2012年3月-2015年3月我院收治高胆红素血症患者36例为研究对象，根据患者是否接受血浆吸附治疗分为治疗组和对照组，每组18例。对照组采用常规方法治疗，治疗组在对照组基础上采用血浆胆红素吸附治疗，比较治疗组治疗前后肝功能及两组患者胆红素、治疗结局。结果 经治疗后，治疗组血浆吸附治疗后血清TBIL明显下降，PTA明显上升（P＜0.05），ALT和PLT水平下降程度不明显。两组治疗后TBIL均有所下降，治疗组与对照组比较差异均有显著性（P＜0.05），以治疗后2周最为明显，表明血浆吸附治疗2周对血清胆红素的清除能力最强 治疗组最终发生重型肝炎2例，占（5%），无一例死亡,对照组最终发生重型肝炎10例，占（25%），死亡4例，占（10%）。结论 血浆胆红素吸附在高胆红素血症中治疗可协助提高临床疗效，改善患者预后，具有较高临床应用价值。 【关键词】血浆胆红素吸附；高胆红素血症；治疗 【中图分类号】R874.2【文献标识码】A【文章编号】1001-5213(2016)09-0116-01 [Abstract] Objective To investigate the plasma bilirubin adsorption treatment effect in hyperbilirubinemia. Methods a total of March 2012 March 2015 our hospital hyperbilirubinemia treated patients with 36 cases as the research object, according to whether the patient received the treatment of plasma adsorption were divided into treatment group and control group, 18 cases in each group. Patients in control group were treated with conventional therapy, treatment group in the control group based on the use of plasma bilirubin adsorption therapy, compared with the treatment group before and after treatment of liver function and two groups of patients with bilirubin, treatment outcome. The results after treatment, the serum levels of TBIL decreased significantly in treatment group, the treatment of plasma adsorption, PTA was increased (P lt; 0 0.05), have no obvious influence on the reduction in the levels of ALT and PLT. TBIL have been declined after treatment in the two groups, treatment group and control group compared the differences were significant (P lt; 0.05), 2 weeks after treatment was the most obvious, indicating that plasma adsorption in the treatment of 2 weeks on serum bilirubin scavenging capacity of the strongest Treatment group occurred in the end of severe hepatitis in 2 cases, accounting for (5%), no deaths, controls the final 10 cases of severe hepatitis, (25%), death in 4 cases,