超声引导射频消融治疗肝脏恶性肿瘤的临床研究.docVIP

精品论文 参考文献 超声引导射频消融治疗肝脏恶性肿瘤的临床研究 湖南省岳阳市一人民医院超声科 湖南岳阳 414000 【摘 要】目的：探讨超声引导射频消融治疗肝脏恶性肿瘤的临床效果。方法：选取29例肝癌患者作为研究对象，所有患者均采取超声引导射频消融治疗；根据患者的治疗情况、并发症发生情况、症状缓解情况、肿瘤消融情况、甲胎蛋白变化情况，综合评价患者的临床效果。结果：29例肝癌患者均顺利完成超声引导射频消融治疗，未出现严重并发症，如腹腔大出血、脓肿、全身性疾病等；随访半年期间，12例患者症状消失，占41.38%；15例患者症状减轻，占51.72；2例患者症状不变，占6.90%；11例患者甲胎蛋白水平降低至正常，占37.93%；15例患者甲胎蛋白水平降低，占51.72%；3例患者甲胎蛋白水平不变，占10.34%；瘤体直径＜3cm有7个，完全坏死6个；瘤体直径4～5cm有20个，完全坏死13个；瘤体直径＞5cm有14个，完全坏死8个；总坏死率为65.85%。结论：超声引导射频消融治疗肝脏恶性肿瘤的临床效果显著，可显著缓解病情，改善症状、抑制病情进展，具有操作简便、安全性高、并发症少等特点，但应严格评估治疗适应症、规范操作，进一步提高疗效及安全性。 【关键词】肝脏恶性肿瘤；超声引导；射频消融 Clinical study of radiofrequency ablation of liver cancer in ultrasound-guided Caochuang Yueyang City，Hunan Province Peoples Hospital，a Department of Ultrasound，Yueyang，Hunan 414000 [Abstract] Objective：To investigate the ultrasound-guided radiofrequency ablation of liver cancer clinical effect. Methods：29 cases of liver cancer patients for the study，all patients were taken by ultrasound-guided radiofrequency ablation；according to the patients treatment，the incidence of complications，symptoms，the tumor ablation，the AFP changes，comprehensive evaluation of the patient clinical results. Results：29 patients with HCC were successfully ultrasound-guided radiofrequency ablation，no serious complications，such as abdominal bleeding，abscesses，systemic diseases；during six months of follow-up，12 patients with symptoms，accounting for 41.38%；15 patients symptoms mitigation，51.72；2 patients symptoms unchanged，accounting for 6.90%；11 cases of AFP decreased to normal levels in patients，accounting for 37.93%；15 cases of alpha-fetoprotein levels were reduced，accounting for 51.72%；3 patients AFP unchanged，accounting for 10.34%；tumor diameter lt;3cm there are 7，6 complete necrosis；tumor diameter 4 ~ 5cm 20，complete necrosis 13；tumor diametergt; 5cm 14，complete necrosis 8；total necrosis rate was 65.85%. Conclusion：Ultrasound guided radiofrequency ablation of liver cancer significant clinical effect，can significantly alleviate the condition，impr