冠心病介入治疗_吴永健演示文稿.ppt

下载文档 降价啦

0
0
约6.6千字
约 55页
2018-02-23 发布于天津
举报
版权申诉
保障服务

冠心病介入治疗_吴永健演示文稿.ppt

1、本文档共55页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。

演示文稿演讲PPT学习教学课件医学文件教学培训课件

Outcomes Primary Composite of Death, new MI or Stroke at 6 mo. Secondary Composite of: Death, new MI or refractory ischemia Death, new MI, stroke, refractory ischemia or repeat revascularization Stroke Baseline Characteristics Early N=1,593 Delayed N=1,438 Age 65.1 65.8 % Female 34.8 34.7 Diabetes 26.5 27.3 Prior MI 19.7 20.9 Prior PCI 13.8 14.1 Prior CABG 7.0 7.3 Prior Stroke 7.2 7.5 Ischemic ECG Δ 80.5 79.9 Elevated Biomarker 77.2 76.9 Primary and Secondary Outcomes Early N=1,593 Delayed N=1,438 HR 95% CI P Death, MI, Stroke 9.7 11.4 0.85 0.68-1.06 0.15 Death, MI, refractory ischemia 9.6 13.1 0.72 0.58-0.89 0.002 Death, MI, Stroke, refractory ischemia + repeat intervention 16.7 19.7 0.84 0.71-0.99 0.039 Death 4.9 6.0 0.81 0.60-1.11 0.19 MI 4.8 5.8 0.83 0.61-1.14 0.25 Stroke 1.3 1.4 0.90 0.48-1.68 0.74 Ref. Ischemia 1.0 3.3 0.30 0.17-0.53 0.00001 Rep. Intervention* 8.8 8.6 1.04 0.82-1.34 0.73 *At 30 days: 5.9 vs 4.2%, HR 1.39, 95% CI 1.00-1.95, P=0.047 Primary Outcome Death, MI, or Stroke Days Cumulative Hazard 0.0 0.02 0.06 0.10 0 30 60 90 120 150 180 Death/MI/Stroke at 180 days Early No. at Risk Delayed Early 1438 1328 1269 1254 1234 1229 1211 1593 1484 1413 1398 1391 1382 1363 Delayed HR 0.85 95% CI 0.68-1.06 P= 0.15 Secondary OutcomeDeath, MI, or refractory ischemia Days Cumulative Hazard 0.0 0.04 0.08 0.12 0 30 60 90 120 150 180 Death/MI/RI at 180 days Delayed Early No. at Risk Delayed Early 1438 1303 1243 1230 1209 1205 1187 1593 1485 1417 1402 1394 1386 1366 HR 0.72 95% CI 0.58-0.79 P=0.002 GRACE Risk Score: Primary Outcome HR 1.14 95% CI 0.82-1.58 P=0.43 HR 0.65 95% CI 0.48-0.88 P=0.005 Interaction P=0.0097 Low/Int Risk GRACE Score 140 N=2070 High Risk GRACE Score = 140 N=961 Death, MI or Stroke at 6 mo. Conclusions Overall, we found no significant difference between an early and a delayed invasive strategy for prevention of death, MI or stroke (primary outcome). However, in the subgroup at highest risk (GRACE score 140), an early invasive str