药学论文浅析中药毒性及其内涵.docVIP

浅析中药毒性及其内涵 梁琦。谢呜 北京中医药大学国家重点方剂学学科，北京 摘要：基于中医理论与临床运用经验为背景的中药毒性有自身特殊内涵。本文从历史与逻辑的角度，在追溯中医“药毒”概念内涵的基础上，分析比较了西医和中医关于药毒的不同理解。提出中药在运用中涉及诸多调控要素和中药成分及作用的复杂性。中医关于中药毒性的认识与西医对药物毒性的认识有所不同，简单套用现代药毒的概念和研究思路来研究中药毒性是不适宜的。药毒的相对性决定了将有更多的中药毒性被发现。现代中药毒性的研究应在药毒内涵界定的基础上，更加重视中药性能与毒性、中药配伍与毒性、方药毒性与病证关系的研究。 关键词：药物毒性；中医药；方剂 Analysis of toxicity of traditional Chinese herbal medicine and its connotation Abstract：Based on lraditionaI Chinese medicjne theory and C|inicaI experience，tradilionaI Ohinese herbaId rug toxicity has jlS own special connotation．From the perspective 0f history and logiC。lhe differenlcomprehension of toxicity between Western medicine and traditionaI Chinese mediciRe was discussed afterretracing the meaning of”drug toxicity”in traditionaI Chinese medicine．The aulhors suggest that it’S notfeasible to study lhe Chinese medicine coping mechanica||Y and applying indiscriminateIY the concept and lheresearch idea about modern drug toxicity since there iS different understanding 0f”drug toxicity”betweenlraditionaI Chinese medicine and Western mediCine．Many controI elements are involved in the use oftraditionaI Chinese herbaI drugs。and Chinese drug components and actions are complex as compared With Western drugs．More and more drugs With{oxicity W#8943;be found due to lhe relativity 0f drug foxicity．Currently。lhe study 0f Chinese drug toxicity shouId pay more attention to fhe relation between the loxicity andChinese drug natu patibilitV and the corresponding disease or syndrome pattern after making definition0f Chinese drug toxicity and its connotation． Keywords：drug toxicity；traditional Chinese herbal drug；Chinese medical formula 效毒二重性是药物作用的基本特性。随着临床中药不良反应的日益增加，中药运用的安全性问题愈来愈受到重视。基于不同学理背景，有关中药毒性目前存在不同角度的理解，其中有些认识则表现出泛化或简单化的倾向，影响了中药毒性研究的开展和深入。因此，梳理和澄清中医药毒的概念内涵是必要的。本文基于中医药的学理与经验，从历史与逻辑的角度，试对中药的毒性内涵及特点进行分析探讨。冀为开展中药毒性的现代研究提供参考。论文发表毕业论文 1 中药“毒”的沿革及其内涵 1．1 古代中药毒性的内涵 1．1．1 药物与毒药同义 古代。药毒不分．混称为毒药．认为凡治病之药皆为毒药。《周礼》有“医师，掌医之政令．聚毒药以供医事”的记载；《素问#8226;藏气法时论》有“毒药攻邪。五谷为养。五果为助#8943;”之论述；唐