Makale Kodu Article Code KVFD商品代码.pdfVIP

Kafkas Univ Vet Fak Derg RESEARCH ARTICLE 17 (4): 609-614, 2011 DOI:10.9775/kvfd.2011.4326 Determination of Lactic Acid Production and Antagonistic Activity against Helicobacter pylori of L. delbrueckii subsp. bulgaricus and S. thermophilus Strains [1] Belma ASLIM * Dilsad ONBASILI **  Zehra Nur YUKSEKDAG *** [1] This research has been supported by TUBITAK through project no: TBAG-2090 (101T129) and FEF Gazi University BAP project no: 05/2002-65 * Gazi University, Molecular Biology Research Center, TR-06830 Gölbaşı, Ankara - TURKEY ** Erciyes University, Faculty of Pharmacy, Department of Pharmaceutical Biotechnology TR-38039 Kayseri - TURKEY *** Gazi University, Faculty of Science and Arts, Department of Biology, TR-06500 Teknikokullar, Ankara - TURKEY Makale Kodu (Article Code): KVFD-2011-4326 Summary In this study, lactic acid production was determined of a total of 32 strains of lactobacilli and streptococci. Different amounts of lactic acid were produced by strains studies; however, lactic acid levels were 13.4 to 18.6 mg/mL for Lactobacillus delbrueckii subsp. bulgaricus strains and 0.6 to 11.5 mg/mL for Streptococcus thermophilus strains. Antimicrobial activity was tested against Helicobacter pylori ATCC 43504. The some strains were able to inhibit H. pylori. Bacteriocin-like substances (BLS) producing strains were determined under conditions eliminating the effects of organic acids. As a result, it was observed that inhibitory activities of only ten strains were due to bacteriocin-like substances. Keywords: L. delbrueckii subsp. bulgaricus, S. thermophilus, Lactic acid, Antimicrobial activity, Helicobacter pylori L. delbrueckii subsp. bulgaricus ve S. thermophilus Suşlarının Helicoba