原创力文档drug discovery of neurodegenerative disease through network pharmacology approach in herbs：（神经退行性疾病的药物发现药草通过网络药理学的方法）.pdfVIP
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drug discovery of neurodegenerative disease through network pharmacology approach in herbs：（神经退行性疾病的药物发现药草通过网络药理学的方法）
Biomedicine Pharmacotherapy 78 (2016) 272–279
Available online at
ScienceDirect
Original article
Drug discovery of neurodegenerative disease through network
pharmacology approach in herbs
a a a a a a
Zhipeng Ke , Xinzhuang Zhang , Zeyu Cao , Yue Ding , Na Li , Liang Cao ,
a a a a b,*
Tuanjie Wang , Chenfeng Zhang , Gang Ding , Zhenzhong Wang , Xiaojie Xu ,
Wei Xiaoa,**
a National Key Laboratory of Pharmaceutical New Technology for Chinese Medicine, Kanion Pharmaceutical Corporation, Lianyungang, China
b Beijing National Laboratory for Molecular Sciences (BNLMS), State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry
and Molecular Engineering, Peking University, Beijing, China
A R T I C L E I N F O A B S T R A C T
Article history: Neurodegenerative diseases, referring to as the progressive loss of structure and function of neurons,
Received 26 August 2015 constitute one of the major challenges of modern medicine. Traditional Chinese herbs have been used as a
Received in revised form 8 January 2016 major preventive and therapeutic strategy against disease for thousands years. The numerous species of
Accepted 13 January 2016
medicinal herbs and Traditional Chinese Medicine (TCM) compound formulas in nervous system disease
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