320排CT全脑灌注成像在TIA诊断中的价值PPT.pptx

Whole brain CT perfusion deficits using 320-detector-row CT scanner in TIA patients are associated with ABCD2 scoreInternational Journal of Neuroscience, 2014; 124(1): 56–60MethodsDiscussionResultsConclusionIntroduction0305040201IntroductionA transient ischemic attack (TIA) is considered a cerebral ischemic event without end organ damage or loss of brain tissue . Despite newer guidelines differentiating TIA from stroke, there remains controversy between a “time-based” and “tissue-based” definition of TIA . Responsible blood vessels for internal carotid artery system of TIA patients mainly for hemiplegia, aphasia and partial body feels obstacle and so on.Responsibility for vertebral artery vessels system mainly displays in the patients with TIA vertigo, double vision, difficulty swallowing, etcTIA inspection method Whole blood viscosity, plasma viscosity, hematocrit 1. Blood rheologyCarotid ultrasound、DSA、Cerebral perfusion2.CerebrovascularCervical spine X-rayCTandMRI 3.CervicalcheckWith the exception of hemorrhagic disease。4.CTandMRITo rule out:Frequent atrial fibrillation, premature beat, old myocardial infarction5.ElectrocardiogramDWI are not the bestSeveral papers demonstrate the presence of DWI/ADC changes in patients with TIA. However, recent evidence has demonstrated that there can be more than just brain ischemia or at least sustained ischemia involved in an acute TIA, which complicates the idea of TIA without detectable tissue damage. Others contend that the somewhat reversible nature of DWI/ADC changes indicates that DWI/ADC may not be the ideal indicator of end organ tissue damage . Because MRI diffusion weighted imaging information infers at least “potential infarction,” where tissue can no longer be saved, rather than ischemia, perfusion imaging either via MRI or CT is used to determine tissue at risk but not yet infracted, also known as penumbra. Perfusion modalities give a better representation of penumbra or tissue at risk but have not infarcted .A