(精编)【医学教学课件】消化系统药物教学课件.pptVIP

Chapter 5;Outline;3;Section 3;Common Prokinetics;;Prokinetics;　Metoclopramide (甲氧氯普胺);Metoclopramide;13;Cisapride;　Cisapride (西沙必利);2-cis isomers in clinic ;Metabolism of Cisapride;Cisapride in Clinic;In Clinic;Cisapride in Clinic;New “Pride” Prokinetic Drugs;22;Domperidone (多潘立酮);Anti-dopaminergic drug;Domperidone’s action;For oral dosage form (tablets): Treatment of gastrointestinal motility disorders: Adults—10 milligrams (mg) three to four times daily. Some patients may require higher doses up to 20 mg three or four times daily. Nausea and vomiting: Adults—20 milligrams (mg) three to four times daily. ;Section 4;Adjuvant for Hepatic Diseases;Common drugs;　Bifendate (联苯双酯);Development ; Deoxyschizandrin γ-Schizandrin Schizandrin Aomisin Pseudo-γ-Schizandrin Schisantherin A Neoschisandrin Schisandrol Schisantherin ;Development of Bifendate ;Development ;Physico-chemical property;Quantitative determination is the formation of a red-purple colouration when chromotropic acid in 75% sulfuric acid reacts with formaldehyde. The colouration is specific to this aldehyde (not produced from ketones and carboxylic acids).;Pharmacologic action;Liu Geng-tao;Chemical synthesis;Analogue of Bifendate;41;Silibinin (水飞蓟宾, 益肝灵);Silibinin in clinic;44;Adjuvant for Biliary Diseases;　Ursodeoxycholic Acid(熊去氧胆酸);Ursodeoxycholic Acid; Isomer;Chemical synthesis;50;exercise（1）;exercise（2）;Case study;Questions ;answer;answer