138例药物性肝损害回顾性调查研究.pdfVIP

• 204 • ( ) 中华中医药杂志 原中国医药学报 2011年1月第26卷第1期 CJTCMP , January 2011, Vol . 26, No.1 ·临床报道· 138例药物性肝损害回顾性调查研究 徐春军，郭宇博，丁伟航1 2 3 1 2 3 （首都医科大学附属北京中医医院，北京 100010； 中华中医药学会，北京 100029； 北京中医药大学， 北京 100029 ） 摘要： 目的：探讨药物性肝损害的证候学特点，分析引起药物性肝损害的因素和治疗方法。方法：按照药物 性肝损害诊断标准对138例药物性肝损害患者 的临床资料进行了回顾性分析，运用证候学将各种药物引起的药物 性肝损害进行归类，探讨药物性肝损害的证候规律。药物性肝病的病因在于湿、毒、瘀、虚，病位主要在肝胆 脾肾，病性属虚实夹杂，病机关键为湿热阻滞肝胆，临床治疗突出利湿退黄的治疗原则，能够有效治疗药物性 肝损害。 关键词：药物性肝损害；证候学；回顾性分析 Retrospective study on 138 cases drug-induced liver injury 1 2 3 XU Chun-jun , GUO Yu-bo , DING Wei-hang 1 2 ( Beijing Hospital of TCM Affi liated to Capital University of Medical Sciences, Beijing 100010, China ； Association of Chinese Medicine, Beijing 100029, China 3Beijing University of Chinese Medicine, Beijing 100029, China) ； Abstract: Objective: To investigate the syndrome characteristic of drug-induced liver injury, and to analyze the factors of drug-induced liver injury and the methods of treatment. Methods:To analyze retrospectively the clinical materials of 138 cases of drug-induced hepatitis according to the standard of drug-induced liver injury, and to classify those cases Induced by different drugs by theory of syndrome,and to investigate the r