异甘草酸镁对重型肝炎患者肝脏储备功能的影响.pdfVIP

2012 年 3 月第 9 卷第 9 期 临床研究 异付草酸镁对重型肝炎患者肝赃储备功能的影响 徐江海 张国柄 翁俊华 河南省安阳市第五人民医 院感染科 河南安阳 455000 [摘要] 目的 探讨 异 甘 草酸镁对重型肝炎患者肝脏储备功能的 影响 D 方法 将 105 例重型肝炎患者随机分为治疗组 n = 56 )和对照组 n = 49 ) 两组均采用综合 内科治疗 治疗组加 用异 甘 草酸镁 200 mg 静滴 1 d/次 疗程为 4 周 D 观 察 两组治疗前后肝功能和肝脏储备功能 变化 并将所 有病例分型 ~分期 比较各组病死率变化 D 结果 经过 4 周治 疗 治疗组肝功能好转 程度 与对照组比较 差异有统计学意义 P 0.05 ): 肝脏储备功能 检查 : 凝血酶原活动 度 PTA )~胆碱酯酶 CHE )比较 两组差异有统计学意义 P 0.05 ) 清蛋白两组比较差异无统计学意义 P 0.05 )D 治 疗组病死率为 51.8% 对照组为 75.5% 治疗组病死率明显低 于对照组 差异有统计学意义 P 0.05 )D 结论 异 甘 草酸镁可显著 改善重型肝炎肝功能 提 高肝脏储备功能 降低病死率 D [关键词] 重型肝炎 异甘草酸镁 肝脏储备功能 预后 中日分类号 文献标识码 文童编号 [ ] R575 [ ] A [ ] 1673-7210 2012 03 c -0057-03 Effects of Magnesium Isoglycyrrhizinate on hepatic reserve function in se vere hepatitis patients XU JiCnglCi ZHANG Guobing WENG JunluC Department of Infectious Diseases. the Fifth People*s Hospital of Anyang City. He*nan Province. Anyang 455000. China [abstract] Objective To investigate the effects of Magnesium Isoglycyrrhizinate on hepatic reserve function in severe hepatitis patients. Methods 105 cases of severe hepatitis patients were divided into treatment group (n = 56) and control group (n = 49). both groups were received comprehensive medical treatment and the treatment group were plus received in jection of Magnesium Isoglycyrrhizinate of 200 mg per day for 4 weeks. The changes of liver function and hepatic reserve function were observed. and the fatality rate of the two groups was compared. Results The improvement of the liver func tion in the treatment group was b