金苇胶囊联合eswl治疗输尿管结石湿热蕴结的临床分析-clinical analysis of jinwei capsule combined with eswl in treating ureteral calculi with damp-heat accumulation.docxVIP

中文摘要目的：观察金苇胶囊联合体外冲击波碎石术治疗输尿管结石(湿热蕴结)的临床疗效及安全性。方法：采用随机、双盲、对照的方法，将72例湿热蕴结型输尿管结石患者随机分为两组即试验组（金苇胶囊联合ESWL术）和对照组（安慰剂联合ESWL术），每组36例，试验组采用金苇胶囊联合ESWL术，对照组用安慰剂联合ESWL术，经过1个疗程(3周)治疗后，观察各组患者中医症状评分、泌尿系B超检查。所有结果均采用SPSS16.0进行统计分析，P≤0.05表示差异有统计学意义。结果：本研究中痊愈率91.18%、有效率5.88%、无效率2.94%，对照组痊愈率71.88%、有效率18.75%、无效率9.37%，两组分级疗效比较及痊愈率组间比较，差异有统计学意义，两组总有效率组间比较，差异无统计学意义。中医证候疗效中临床痊愈7例（20.59％），显效21例（61.76％），有效5例（14.70％），无效1例（2.94％），对照组痊愈2例(6.25％)，显效11例(34.38％)，有效13例（40.63％），无效6例（18.75％），两组分级证候疗效、愈显率及总有效率比较，差异有统计学意义。与对照组比较，试验组在中医症状评分、碎石次数、结石排净的时间及肉眼血尿持续时间等方面疗效优于对照组，差异有统计学意义。结论：金苇胶囊联合ESWL术治疗湿热蕴结型输尿管结石有效，能改善其临床症状，提高疾病的痊愈率，未见明显不良反应。关键词金苇胶囊湿热蕴结输尿管结石临床疗效安全性ABSTRCTObjective:ToobservetheJin-weicapsulecombinedwithextracorporealshock-wavelithotripsytreatingureteralstones(damp-heataccumulationtype)intheclinicalefficacyandsafety.Methods:Arandomized,double-blind,placebo-controlledmethod,72casesofdamp-heataccumulationtypeureteralstoneswererandomlydividedintotwogroupsnamelyexperimentalgroup(Jin-weicapsulecombinedESWLsurgery)andcontrolgroup(placebocombinedESWLsurgery),eachgourphas36cases,thetestgroupweretreatedwithJin-weicapsulecombinedESWL,patientsinthecontrolgroupweretreatedwithplacebocombinedESWLpatients,afteracourseoftreatment(3weeks),eachgroupwasobservedinTCMsymptomscore,urinaryultrasound.AllresultsareusedSPSS16.0statisticalanalysis,P≤0.05indicatedthatthedifferencewasstatisticallysignificant.Results:Inthisstudy,thecurerate91.18%,efficiency5.88%,theinefficiencyof2.94%,inthecontrolgroupthecurerate71.88%,efficiency18.75%,theinefficiencyof9.37%,thecomparisonofclassificationefficacyandthecureratebetweenthetwogroups,thedifferencewasstatisticallysignificance,thetotaleffectiveratebetweenthetwogroups,thedifferencewasnotstatisticallysignificant.TCMclinicalefficacyin7casesrecovered,accountingfor20.59%,excellencein21cases,accountingfor61.76%,effectivein5cases,accountingfor14.70%,ineffectivein1case,accountingfor2.94%,inthecontrolgrouprecoveredin2cases,accountingfor6.25%,excellencein11cases,accountingfor34.38%,effectivei