临床因素涎腺粘液表皮样癌预后的影响一项回顾性研究.-clinical factors influencing the prognosis of mucoepidermoid carcinoma of salivary gland a retrospective study..docxVIP

SIGNATURES OF SUPERVISOR (S) Principal researcher …………………………………………………………………. Signature…………………………………………Date……………………………… Supervisor…………………………………………………………………………….. Signature………………………………………Date………………………………... Supervisor ……………………………………………………………………………… Signature………………………………………….Date……………………………… COPYRIGHT I,………………………………………………………………………………………… …………………do hereby declare that the thesis of my research is a copyright of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China. ABBREVIATIONS MEC : Mucoepidermoid carcinoma OS : Overall survival DFS : Disease free survival LG : Low grade IG : Intermediate grade HG: High grade MSG : Major salivary gland MISG : Minor salivary gland SMG: Submandibular gland SLG : Sublingual gland Sx: Surgery RT: Radiotherapy LN : Lymphnode LIST OF CONTENTS HYPERLINK \l _TOC_250009 LIST OF TABLES AND FIGURES 1 PART I – ABSTRACT 2 PART II - DISSERTATION: HYPERLINK \l _TOC_250008 Introduction 4 HYPERLINK \l _TOC_250007 Aims and objectives 7 HYPERLINK \l _TOC_250006 Materials and Methods 8 HYPERLINK \l _TOC_250005 Results 10 HYPERLINK \l _TOC_250004 Discussion 20 HYPERLINK \l _TOC_250003 Conclusion 27 Kaplan – Meier graph 28 Reference 32 PART III - REVIEW OF LITERATURE: Background 37 Anatomy 37 HYPERLINK \l _TOC_250002 Histogenesis 39 HYPERLINK \l _TOC_250001 Review of literature 41 Reference 69 HYPERLINK \l _TOC_250000 ACKNOWLEDGEMENTS 75 华 中 科 技 大 学 硕 士 学 位 论 文 PAGE 1 PAGE 1 LIST OF TABLES AND FIGURES Table 1: Characteristic of patient with MEC 10 Table 2: Demographic details 12 Table 3: Relationship between tumor grade and treatment modalities 15 Table 4: Results of univariate analysis 19 Figure 1: Kaplan- Meier graph for overall survival and disease free survival 16 Figure 2: Kaplan- Meier graph of overall survival for age group 28 Figure 3: Kaplan-Meier graph of disease free survival for age group 28 Figure 4: Kaplan- Meier graph of overall survival for gender 29 Figure 5: Kaplan- Meier gr