异舒吉治疗急性心肌梗死合并急性左心衰临床观察.docVIP

异舒吉治疗急性心肌梗死合并急性左心衰临床观察 　　摘 要 目的：评价异舒吉泵入治疗老年急性心梗合并急性左心衰的疗效和安全性。方法：选择急性心梗合并急性左心衰的老年患者20例。在常规治疗的基础上，加用异舒吉注射液50mg，通过输液泵静脉输注，疗程5天。用药后3天及5天观察临床疗效及安全性。结果：治疗3～5天后，临床总有效率分别达到85%和90%。1例患者治疗2天后死亡。治疗3天后，左心室射血分数(LVEF)增高10例、脑尿钠肽(BNP)降低20%12例。治疗5天后，LVEF增高14例、BNP降低20%16例。结论：异舒吉泵入治疗老年急性心梗合并急性左心衰有较强的纠正心力衰竭的疗效，不良反应小，安全可靠。 　　摘 要 目的：评价异舒吉泵入治疗老年急性心梗合并急性左心衰的疗效和安全性。方法：选择急性心梗合并急性左心衰的老年患者20例。在常规治疗的基础上，加用异舒吉注射液50mg，通过输液泵静脉输注，疗程5天。用药后3天及5天观察临床疗效及安全性。结果：治疗3～5天后，临床总有效率分别达到85%和90%。1例患者治疗2天后死亡。治疗3天后，左心室射血分数(LVEF)增高10例、脑尿钠肽(BNP)降低20%12例。治疗5天后，LVEF增高14例、BNP降低20%16例。结论：异舒吉泵入治疗老年急性心梗合并急性左心衰有较强的纠正心力衰竭的疗效，不良反应小，安全可靠。 　　关键词 异舒吉 急性心梗 急性左心衰 临床观察 　　关键词 异舒吉 急性心梗 急性左心衰 临床观察 　　doi:10.3969/j.issn.1007-614x.2012.05.179 　　doi:10.3969/j.issn.1007-614x.2012.05.179 　　Abstract Objective:To evaluate the curative effect and safety of pumping Isoket on the elderly with acute myocardial infarction(AMI)complicated by acute left ventricular failure(ALVF).Methods:Twenty gerontal patients with AMI complicated by ALVF were chosen and treated with Isoket(50mg)by intravenous infusion through infusion pump in addition to conventional therapy.The course of treatment lasted five days.The curative effect and safety were observed after 3 and 5 days of treatment.Results:The total effective rates were 85% and 90% respectively after 3 and 5 days of treatment.One death occurred after 2 days of treatment.After 3 days of treatment,the number of patients with left ventricle eject fraction(LVEF)increased is 10 and the number of patients with brain natriuretic peptide(BNP)decreased by 20% is 12.After 5 days of treatment,the number of patients with LVEF increased is 14 and the number of patients with BNP decreased by 20% is 16.Conclusion:Pumping Isoket has good curative effect on heart failure for the elderly and offers a safe and reliable approach to treating AMI complicated by ALVF with few side effects. 　　Abstract Objective:To evaluate the curative effect and safety of pumping Isoket on the elderly with acute myocardial infarction(AMI