宁夏地区早发性乳腺癌临床病理特征的分析-analysis of clinicopathological features of early breast cancer in ningxia region.docxVIP

宁夏地区早发性乳腺癌临床病理特征的分析-analysis of clinicopathological features of early breast cancer in ningxia region.docx

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宁夏地区早发性乳腺癌临床病理特征的分析-analysis of clinicopathological features of early breast cancer in ningxia region

ResearchclinicopathologicalfeaturesofEarly-onsetbreastcancerinNingxiaABSTRACTObjectiveAccordingtotheHistopathologicalclassificationandCerb-B-2overexpressionofBreastCancerpatientsinNingxia,theoptimalageatdiagnosiswasidentifiedtodifferentiatetheearly-onsetbreastcancerpatients.Theassociationsbetweentheageatdiagnosisandclinicopathologicalfeatureswereanalyzed,Thesewillprovidethereferenceforclinicalindividualizedtreatmentandprognosisjudgment.Method1767caseswithbreastcancerinNingxiaMedicalUniversityGeneralHospitalwereanalyzed,whichwerestratifiedinto6groupsbyagerangeof5yearsfrom30to50yearsandjustifiedwhichagewasthebestresectionforassociationbetweenhistologicgradeandCerb-B-2.Inaddition,theassociationbetweenearlybreastcancerandotherclinicopathologicalfactorswereanalyzed.ResultTheassociationbetweenhistologicgrade3andCerb-B-2overexpressionwasonlyseeninwomenage≤35years.≤35yearswillbedefinedastheparoxysmageofearly-onsetbreastcancer.Theearly-onsetbreastcancerweremorelikelyCerb-B-2overexpression,largetumorsize,highhistologicgrade,axillarylymphnodemetastasis,lowhormonereceptorexpressionandsoon,Buthasnothingtodowithnationalcharacteristics.Conclusion1.Theonsetofage≤35yearshasgoodrepresentativeasearlybreastcancer.2.Early-onsetbreastcancerassociatedwithpartoftheclinicopathologicalfeatures.3.Earlybreastcancerhavemoreaggressiveandhighermalignantdegree.Keywords:Early-onsetbreastCancer;Estrogenreceptor;Progesteronereceptor;Cerb-B-2;ki-67英文缩略词表英文全称中文全称AJCCAmericanJointCommitteeonCancer美国癌症联合会WHOWorldHealthOrganization世界卫生组织ERestrogenreceptor雌激素受体PRprogesteronereceptor孕激素受体IHCImmunohistochemistry免疫组织化学SPSSStatisticalPackagefortheSocialScience社会科学统计软件EOBCEarly-onsetbreastcancer早发性乳腺癌目录摘要.............................................................Ⅰ英文摘要.........................................................Ⅱ缩略词...........................................................Ⅲ前言..............................................................1材料和方法.......................................................

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