北京市大兴区学龄儿童抽动障碍相关危险因素病例对照研究.docVIP

北京市大兴区学龄儿童抽动障碍相关危险因素病例对照研究 　　【摘 要】 目的:了解学龄儿童抽动障碍(tic disorders,TD)致病的危险因素,探索早期干预方法。方法:采用分层整群随机抽样法,从大兴区41597名小学生和20239名初中生中抽取4020名学生进行TD的横断面调查。采用自编抽动障碍初筛问卷和一般情况调查表收集学生临床资料,对筛查阳性者及老师或同学报告有类似症状者进行面谈和临床评估,采用美国《精神障碍诊断与统计手册》第四版中TD标准进行诊断和分类,最终查出TD患儿(病例组)86例。抽取与病例组年龄、性别和年级相匹配的TD阴性者86例为对照组。通过电话访谈来确定家族中的TD可疑病例,然后对可疑病例进行面访以排除或确诊TD。采用自编定式病历表调查与抽动症发病相关的因素。结果:抽动症家族史(7.0%)、剖腹产史(如86例TD患者中,剖腹产出生者31例,占36.0%)、碳酸饮料(10.5%)、肥胖(14.0%)和病前心理应激是TD发病的危险因???(均P 　　【关键词】 抽动障碍;学龄儿童;相关因素;多因素分析;病例对照研究 　　中图分类号:R748,R749.94 文献标识码:A 文章编号:1000-6729(2010)001-0047-05 　　doi:10.3969/j.issn.1000-6729.2010.01.011 　　 　　Related factors of tic disorders among schoolchildren in Daxing district of Beijing:a cose-control study 　　LIU Yong-Yi?1,ZHENG Yi2,HAN Shu-Wen?1,CUI Yong-Hua?2,YANG Zhe?1 　　?1Mental Rehabilitation Center,Daxing Mental Hospital,Beijing 102600,China 　　?2Beijing Anding Hospital,Capital Medical University,Beijing 100088,China 　　Corresponding author:ZHENG Yi,E-mail:yizheng@ccmu.省略 　　【Abstract】 Objective:To understand the related factors of tic disorders(TD) and early intervention among schoolchildren.Methods:Using stratified-cluster random sampling techniques,4,020 children were selected from 61,836 schoolchildren in Daxing district of Beijing.Totally 4,020 children and their parents were asked to fill in a self-designed questionnaire covering both motor and vocal tics and general information.A three-stage procedure was used:screening,interview and clinical investigation.A total of 3,813 children were investigated successfully.The children who were reported with tic symptoms as well as those who were reported by their teachers or classmates were surveyed according to the TD criteria in Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition(DSM-Ⅳ).Eighty-six TD children were investigated respectively about the related factors of TD,and 86 healthy children matched in age,sex and grade were selected as controls.Telephone interview was carried out to find the doubtful TD cases i