治疗下呼吸道感染3种方案成本-效果分析.docVIP

治疗下呼吸道感染3种方案成本-效果分析 　　[摘要] 目的：对治疗下呼吸道感染的3种用药方案进行临床疗效与成本-效果分析，从而寻找最佳治疗方案，指导临床更合理地选择和用药。方法：选择144例下呼吸道感染患者，随机分为A、B、C 3组，每组48例，A组给予哌拉西林钠舒巴坦钠3.0 g，qd；B组给予头孢呋辛钠1.5 g，tid；C组给予头孢曲松钠1 g，qd，均静脉滴注，疗程为7 d。运用药物经济学的成本-效果分析方法进行药物经济学评价。结果：A、B、C组成本分别为1 116.50、488.46及1 300.88元(P＜0.05)；临床有效率分别为85.42％、79.17％及81.25％(P＞0.05)；成本-效果比分别为13.07、6.17、16.01。结论：从药物经济学的观点分析，B方案是治疗下呼吸道感染较佳的治疗方案。 　　[关键词] 下呼吸道感染；治疗方案；成本-效果分析 　　[中图分类号] R56[文献标识码]A [文章编号]1673-7210（2008）09（c）-011-02 　　 　　Cost-effectiveness analysis of three therapeutic schemes in the treatment of lower respiratory tract infections 　　YANG Xue-mei, WU Qing-huan, LIANG Dan, XIAO Xi-zhou, MA Ling-yan, ZHENG Cui 　　(Medicine Education Ministry, the Second Affiliated Hospital of Zhongshan University, Guangzhou 510120, China) 　　[Abstract] Objective: To analyze the cost-effectiveness of three therapeutic schemes in the treatment of lower respiratory tract infections, and seek for the best therapeutic scheme to guide a better choice and utilization of drug in clinic. Methods: 144 patients with lower respiratory tract infections were selected as the objectives, and then randomly divided into three groups: group A, B and C. Group A was treated with Piperacillin Sodium/Sulbactam Sodium for 3.0 g, qd; group B was treated with Cefuroxime Sodium for 1.5 g, tid; group C was treated with Ceftriaxone Sodium for 1 g, qd, all the drugs were used by intervenous drop infusion, the treatment course was 7 d. The cost-effectiveness analysis of pharmacoeconomics was employed to appraise the pharmacoeconomics effect. Results: The costs of the three therapeutic schemes were 1 116.50 yuan, 488.46 yuan and 1 300.88 yuan(P0.05) respectively; the ratios of cost-effectiveness were 13.07, 6.17 and 16.01 respectively. Conclusion: Analyzed from the viewpoint of pharmacoeconomics, the B scheme is a better choice in the treatment of lower respiratory tract infections. 　　[Key words] Lower respiratory tract infections; Therapeutic schemes; Cost-effectiveness analysi