雷公藤多苷联合他巴唑强松治疗甲亢突眼61例病例分析.docVIP

雷公藤多苷联合他巴唑强松治疗甲亢突眼61例病例分析 　　[摘要] 目的:探讨采用雷公藤多苷联合他巴唑强的松治疗甲亢突眼临床疗效及病例分析。方法:我院61例甲亢突眼住院患者,经雷公藤多苷联合他巴唑强的松治疗后,分析病例并综合评价其疗效。结果:雷公藤多苷联合他巴唑强的松治疗甲亢突眼的治愈率为57.4%,显效率为18.0%,有效率为11.5%,无效率为11.5%。结论:免疫抑制剂雷公藤多苷联合他巴唑强的松综合治疗甲亢突眼,疗效更为明显,可以相应地减少他巴唑强的松的剂量,副作用小,缩短病程。 　　[关键词] 甲亢突眼;雷公藤多苷联合他巴唑强的松;临床疗效;病例分析 　　[中图分类号] R581.1[文献标识码]A [文章编号]1673-7210(2009)08(b)-025-03 　　 　　Case analysis of Tripterygium Wilfordii united Tapazole Prednisone in the treatment of 61 cases of thyrotoxic exophthalmos 　　MU Yadong 　　(Department of Endocrinology, the First Peoples Hospital of Shangqiu City, Henan Province, Shangqiu 476100, China) 　　[Abstract] Objective: To explore the clinical efficacy and case analysis of Tripterygium Wilfordii united Tapazole Prednisone in the treatment of hyperthyroidism exophthalmos. Methods: 61 cases of patients with thyrotoxic exophthalmos in our hospital were given case analysis and comprehensive evaluation after the treatment of Tripterygium Wilfordii united Tapazole Prednisone. Results: The cure rate of Tripterygium Wilfordii united Tapazole Prednisone in the treatment of hyperthyroidism exophthalmos was 57.4%, markedly effective rate was 18.0%, effective rate was 11.5%, non-efficiency rate was 11.5%. Conclusion: Comprehensive treatment of immunosuppressant Tripterygium Wilfordii united Tapazole Prednisone for hyperthyroidism exophthalmos is more evident, and can correspondingly reduce the dosage of Tapazole and Prednisone, and also has small side-effects, and shortens the course of treatment. 　　[Key words] Thyrotoxic exophthalmos; Tripterygium Wilfordii united Tapazole Prednisone; Clinical efficacy; Case analysis 　　 　　甲状腺功能亢进症(简称甲亢)突眼是一种与自身免疫性甲状腺疾病密切相关的特异性自身免疫性眼病,是甲亢的一种难治性并发症,为了提高本病的治疗效果,我院采用雷公藤多苷联合他巴唑强的松综合治疗61例甲亢突眼(GO),现报道如下: 　　1资料与方法 　　1.1一般资料 　??我院住院的61例GO患者,其中,男23例,女38例;男女比为1∶1.65;发病年龄为17～64岁,平均37.48岁。突眼病程3个月(3个月~1年 7例,2～3年31例,4～5年14例,6年或6年以上9例)。全部病例对糖皮质激素无禁忌证(无高血压、糖尿病、消化性溃疡、精神病、骨质疏松、严重感染及肝、肾功能不全等)。 　　1.2 药物 　　雷公藤多苷片(贵州汉方制药有限公司):祛风解毒、除湿消肿、舒筋通络,同时具有抗感染及抑制细胞免疫