清热消银汤联合穴的位埋线治疗血热型寻常型银屑病疗效观察及对t细胞亚群影响.docx

The clinical study of Qingrexiaoyintang combining catgutimplantation at acupoint treating psoriatic of blood-heat type and itsinfluence onT cell subsetsSpecialty:Dermatology,Surgery of TCMTutor:Professor Zhang XiaojieAuthor:Zhang DongmeiAbstractObjective: To observe the clinial effect of Qingrexiaoyintang combining catgutimplantation at acupoint treating psoriatic of blood-heat type and study the infulence ofthis therapeutic method on T cell subsets,probe into its mechanism .Method: 80 cases of psoriasis vulgaris are randomized into two groups---treatmentgroup (Qingrexiaoyintang combining catgut implantation at acupoint group)and controlgroup (Fufangqingdaiwan group).during the 8-week treatment course,observeing the skindistribution range,erythema severity,scale thickness,soakage degree,itching degree and soon,to determine the effect. T cell subsets were observed before and after treatment .Result: Clinical Research：the healing rate and total effective rate of the treatmentgroup are 74.8% and 91.2% respectively while that of the control group are 45.3％and77.65％respectively.There are significant deviation between the two groups(P0.05). Theresults of T cell subsets examination show that before treatment ,the level of CD3+、CD4+、CD4+/CD8+ in Peripheral Blood was lower than the normal,that of the CD8+ was higher.After Qingrexiaoyintang combining catgut implantation at acupoint treating,the level ofCD3+、CD4+、CD4+/CD8+ in Peripheral Blood of 20 psoriasis arised and closed tonormal,There is no evident change in the number of CD8+ before and after the treatment.Conclusion: Qingrexiaoyintang combining catgut implantation at acupoint hasconfirm curative effect of treating psoriasis vulgaris and low recurrence rate.Themechanism of action may be related with its effect of anti-microorganism,regulatingimmunity,anti-inflammatory,antioxidation,improving blood rheology,etc.Key wordspsoriasis of blood-heat; qing re xiao yin tang; catgut implantation atacupoint; T cell ubsets; clinica