网站大量收购独家精品文档,联系QQ:2885784924

深部真菌感染诊断治疗进展课件.ppt

  1. 1、本文档共114页,可阅读全部内容。
  2. 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
  3. 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载
  4. 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
深部真菌感染诊断治疗进展课件

* Objective: The risk of developing invasive aspergillosis increases with increasing levels of immune deficiency. In contrast the risk of allergic aspergillosis is enhanced in individuals whose immune system is hyper-reactive. The two chest X-rays show examples of acute invasive and allergic pulmonary aspergillosis. Aspergilloma - This is a very different disease also caused by the Aspergillus mould where the fungus exploits an existing weakness. The fungus grows within a cavity of the lung, which was previously damaged during an illness such as tuberculosis or sarcoidosis. Any lung disease which causes cavities can leave a person open to developing an aspergilloma. The spores penetrate the cavity and germinate, forming a fungal ball within the cavity. The fungus secretes toxic and allergic products which may make the person feel ill. The picture shows the fungal ball (aspergilloma) which was removed from a lung and measures about 6cm diameter. * It is usually not easy to recognize the terrorist * So it is difficult to recognize them early * One needs instruments to discriminate between potential terrorists and normals persons – this is annoying enough but inevitable * Tools to diagnose loose on specificity with better sensitivity – not uncommon And then there is always the question whether we deal with a pathogen or bystander * * * Finally. the EORTC- IFICG and the MSG (NSAID) have developed a scheme to help integrate this information and assign a diagnosis with a reasonable degree of certainty. Hence. an empirical treatment strategy is essentially therapy initiated for possible invasive aspergillosis whereas pre-emptive therapy is employed to manage probable disease. * * * * * * * * * * * 由于念珠菌感染具有很高的死亡率,所以早期治疗侵袭性念珠菌感染可显著降低患者死亡率。 对自2001年1月至2004年12月的157例念珠菌血流感染患者进行的回顾性、队列研究,比较开始抗真菌治疗的时间与患者死亡率的关系,结果表明:自首次阳性血培养的血标本采集后开始计时,12小时内即给予抗真菌治疗,患者的死亡率仅为11.1%;12小时后才开始抗真菌治疗,患者的平均死亡率高达33.1%(P=0.169)。 参考文献: 4. Morrell M et al. Antimicrob Agents Chemother. 2005;49:3640-3645

文档评论(0)

2017meng + 关注
实名认证
内容提供者

该用户很懒,什么也没介绍

1亿VIP精品文档

相关文档