CIK细胞治疗消化系统肿瘤患者效果观察和护理体会.docVIP

CIK细胞治疗消化系统肿瘤患者效果观察和护理体会 　　（四川成都市龙泉驿区疾病预防控制中心四川成都610100） 　　摘要：目的探讨采用CIK细胞对消化系统肿瘤患者进行免疫治疗的临床疗效以及护理体会。方法选取我院在2010年10月-2012年10月期间收治的78例消化系统肿瘤患者，所选取的患者采取CIK细胞进行免疫治疗以及相应的心理护理，在治疗期间对CIK细胞的制备，治疗中以及治疗后患者的不良反应进行详细的记录，并对患者在出院之后的疗效进行随访。结果78例患者中，胆囊癌3例，其中有近期疗效的患者2例；肝癌4例，其中有近期疗效的患者3例；胰腺癌5例，其中有近期疗效的患者3例；食管癌2例，在治疗之后症状都明显改善。在采用CIK细胞治疗的16例直肠癌、28例结肠癌、20例胃癌患者中，治疗的近期有效率为71.8%、65.6%和77.9%。患者大部分都可以积极的配合治疗，取得了较好的临床疗效。结论采用CIK细胞对消化系统肿瘤患者进行免疫治疗具有较好的临床疗效，而且没有明显的不良反应，是一种有效的治疗手段，值得在临床上进行推广。 　　关键词:CIK细胞；消化系统肿瘤；治疗效果；护理体会Abstract：Objective To investigate the clinical efficacy of CIK cells immunotherapy in patients with tumors of the digestive system as well as nursing experience. Methods From October 2010 -2012 October 78 patients with digestive cancer patients, selected patients to take CIK cells immunotherapy and psychological care, preparation of CIK cells during treatment, treatment and adverse reactions in patients after treatment detailed records of the patients were followed up after discharge treatment.Results Of the 78 patients, three cases of gallbladder cancer, which have a short-term effect of 2 patients; 4 cases of liver cancer, which have a short-term effect of the 3 patients; 5 cases of pancreatic cancer, which have a short-term effect of the 3 patients; esophageal cancer Example symptoms significantly improved after treatment. CIK cell therapy of 16 patients with rectal cancer, 28 cases of colon cancer, 20 patients with gastric cancer, treatment response rate was 71.8%, 65.6% and 77.9%, respectively. The majority of patients can actively cooperate with the treatment, and achieved good clinical efficacy. Conclusion s CIK cells immunotherapy has good clinical efficacy in patients with tumors of the digestive system, and no significant adverse reactions, is an effective treatment, it is worth to promote clinical. 　　Key words：CIK cells;digestive system tumors;therapeutic effect;nursing experience 　　中图分类号: R735文献标识码:A文章编号:1004-4949(2013)05-010-02 CIK细胞，即细胞因子诱导的杀伤细胞(Cytokine-Induced