Transplantation of Haematopoietic Stem Cells（造血干细胞）.pptVIP

Transplantation of Haematopoietic Stem Cells（造血干细胞） ——Obtaining Haematopoietic Stem Cells Haematopoietic stem cells normally reside in the bone marrow(骨髓), with small numbers found in the circulating(流通的) blood. Traditionally, stem cells used for transplantation are obtained directly from the bone marrow by aspirating from the iliac crests（髂嵴；髂骨）. Bone marrow harvesting, while generally well tolerated（可容忍的）, exposes the donor to the risks of general anaesthesia (全身麻醉) and may require hospital admission. In recent years, stem cells collected from the peripheral blood(周边血液) have largely replaced bone marrow as the source of haematopoietic progenitors（先觉着） for autologous(自体的 自体同源的) transplants and now has been increasingly used for allogeneic(同种异体的) transplants. For autotransplants（自身移植物）, stem cells are mobilized（使流通） from chemotherapeutic(化学疗法的) agent, with or without the administration of growth factors. Register your bone marrow. If you can donate your bone marrow when others need it. It equals that you can save a life. * *