心脉隆注射液治疗慢性肺源性心脏病50例例分析.docVIP

心脉隆注射液治疗慢性肺源性心脏病50例病例分析 　　摘 要 目的：研究心脉隆注射液治疗慢性肺源性心脏病的临床疗效。方法：选取100例慢性肺源性心脏病患者随机分为治疗组和对照组各50例。对照组给予常规对症支持治疗，治疗组在对照组的基础上给予心脉隆注射液治疗。比较两组患者临床疗效和不良反应发生情况，以及治疗前、治疗后1周的血浆脑钠肽（BNP）和超声心动图指标包括心率（HR）、心输出量（CO）、心脏指数（CI）、左室短轴缩短率（FS）、左心射血分数（LVEF）的数值变化。结果：治疗组临床疗效明显优于对照组；两组患者治疗前HR、CO、CI、FS、LVEF和血浆BNP比较差异无统计学意义，治疗组治疗后以上指标较治疗前明显改善，且明显优于对照组治疗后；两组患者不良反应比较差异无统计学意义。结论：心脉隆注射液临床疗效显著，可有效改善心功能，且不良反应少。 中国论文网 /6/viewhtm　　关键词 心脉隆注射液 慢性肺源性心脏病 脑钠肽 　　中图分类号：R286； R541.5 文献标识码：B 文章编号：1006-1533（2015）21-0036-03 　　Analysis of Xinmailong injection for the treatment of 50 cases of patients with chronic pulmonary heart disease* 　　SHI Changli**， ZHU Jieyan， DING Yuemei 　　（Department of Respiration， The First Hospital of Jindezhen， Jindezhen 333000， China） 　　ABSTRACT Objective： To discuss the clinical efficacy of Xinmailong injection in the treatment of pulmonary heart disease. Methods： One hundred cases of patients with pulmonary heart disease were randomly divided into a treatment group and a control group with 50 cases each. All the patients were given conventional symptomatic treatment， and the treatment group was given Xinmailong injection in addition. The clinical efficacy and adverse reactions were compared， and the changes of BNP， HR， CO， CI， FS， LVEF were also compared before and one week after the treatment. Results： The clinical efficacy was significantly better in the treatment group than in the control group. The comparison of HR， CO， CI， FS， LVEF and BNP between two groups showed no significant difference before the treatment， however these indexes were significantly improved in the treatment group and better than in the control group after the treatment. The differences of adverse reactions between two groups had not statistically significance. Conclusion： Xinmailong injection has good clinical efficacy and less adverse reaction and can improve the heart function. 　　KEY WORDS Xinmailong injection； chronic pulmonary heart disease； BNP 　　慢性肺源性心脏病又称肺心病，是呼吸内科常见病和多发病之一，发病率高，致残率高，给患者及其家庭、社会